Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ST4052_RS02940 Genome accession   NZ_CP065476
Coordinates   546436..547662 (+) Length   408 a.a.
NCBI ID   WP_002950151.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4052     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 541436..552662
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4052_RS02915 (ST4052_02915) - 542011..543282 (-) 1272 WP_011225668.1 hydroxymethylglutaryl-CoA reductase, degradative -
  ST4052_RS02920 (ST4052_02920) - 543275..544450 (-) 1176 WP_347100918.1 hydroxymethylglutaryl-CoA synthase -
  ST4052_RS02925 (ST4052_02925) - 544772..545632 (+) 861 WP_011226990.1 thymidylate synthase -
  ST4052_RS02930 (ST4052_02930) - 545740..546243 (+) 504 WP_002950147.1 dihydrofolate reductase -
  ST4052_RS02935 (ST4052_02935) - 546248..546418 (+) 171 WP_002886174.1 hypothetical protein -
  ST4052_RS02940 (ST4052_02940) clpX 546436..547662 (+) 1227 WP_002950151.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ST4052_RS02945 (ST4052_02945) yihA 547672..548271 (+) 600 WP_002950154.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ST4052_RS02950 (ST4052_02950) - 548401..549777 (+) 1377 WP_041826987.1 amino acid permease -
  ST4052_RS02955 (ST4052_02955) mmuM 549789..550739 (+) 951 WP_164177973.1 homocysteine S-methyltransferase -
  ST4052_RS02960 (ST4052_02960) - 550852..551106 (+) 255 WP_002950164.1 DUF1912 family protein -
  ST4052_RS02965 (ST4052_02965) - 551178..551537 (+) 360 WP_002950165.1 helix-hairpin-helix domain-containing protein -
  ST4052_RS02970 (ST4052_02970) plsY 551651..552292 (-) 642 WP_002950167.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45063.49 Da        Isoelectric Point: 4.4119

>NTDB_id=509943 ST4052_RS02940 WP_002950151.1 546436..547662(+) (clpX) [Streptococcus thermophilus strain 4052]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREETAEEVLADLAETPKPKELLDILNNYVVGQDRV
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTYLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDESSYMKEIVAEDIQKFGLIPEFIGRLPVLATLEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSLEDVTKVRITKEAVDGK
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=509943 ST4052_RS02940 WP_002950151.1 546436..547662(+) (clpX) [Streptococcus thermophilus strain 4052]
ATGGCTGGAAATCGTAATGAAGAGATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTGAAGAAAATTATCGC
CGGTAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAACGGCTGAAGAAGTTT
TAGCTGACTTGGCTGAAACGCCAAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAAGATCGTGTC
AAACGTGCCTTGGCAGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGATAATGATGTGGA
CTTGCAAAAATCAAATATCCTCATGATTGGACCAACAGGGTCAGGGAAAACTTACTTAGCTCAGACTTTGGCTCGTAGTT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCAGGTTATGTGGGTGAGGATGTGGAAAATATCCTC
CTCAAACTAATTCAAGCGGCAGACTTTAATATTGAACGTGCGGAACGTGGGATTATCTACGTGGACGAGATTGATAAGAT
TGCCAAAAAAGGTGAGAATGTTTCAATCACTCGTGATGTTTCAGGTGAAGGGGTTCAACAAGCTCTCTTGAAGATTATTG
AGGGAACAGTGGCTAGTGTTCCACCTCAAGGTGGTCGTAAACACCCTAATCAAGAGATGATTCAAATTGATACTAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGGTT
TGGTCAAAATAATAAAGCAATTGATGACGAATCATCATACATGAAAGAAATTGTGGCTGAAGATATCCAAAAATTTGGAC
TTATCCCTGAATTTATCGGACGTTTGCCAGTTCTTGCGACCCTTGAACAGTTAACGGTTGACGACTTGGTGCGTATTTTG
ACAGAGCCTAGGAATGCCTTGGTGAAGCAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCCCTTGAGGCTATTGCAAGTAAGGCAATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTTATGTTTGAAATCCCTAGTCTGGAAGATGTCACTAAGGTTCGTATCACCAAAGAAGCTGTTGATGGGAAA
GCTGCTCCAGTATTGGAAACAGCATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-388)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

88.509

100

0.887
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.757

99.755

0.566