Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I5V48_RS02890 Genome accession   NZ_CP065430
Coordinates   587064..587753 (+) Length   229 a.a.
NCBI ID   WP_197315109.1    Uniprot ID   A0A7T1LB30
Organism   Streptococcus suis strain YZDH1     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 582064..592753
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I5V48_RS02865 (I5V48_02865) - 582381..583724 (+) 1344 WP_197315108.1 DEAD/DEAH box helicase -
  I5V48_RS02870 (I5V48_02870) - 583742..583978 (+) 237 WP_029174430.1 DUF4059 family protein -
  I5V48_RS02875 (I5V48_02875) trxB 583992..584909 (+) 918 WP_044760151.1 thioredoxin-disulfide reductase -
  I5V48_RS02880 (I5V48_02880) - 584919..585458 (+) 540 WP_044760152.1 YceD family protein -
  I5V48_RS02885 (I5V48_02885) gndA 585555..586982 (+) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  I5V48_RS02890 (I5V48_02890) covR 587064..587753 (+) 690 WP_197315109.1 response regulator transcription factor Regulator
  I5V48_RS02895 (I5V48_02895) - 587843..588973 (+) 1131 WP_043026138.1 AI-2E family transporter -
  I5V48_RS02900 (I5V48_02900) nrdR 589045..589536 (+) 492 WP_002938341.1 transcriptional regulator NrdR -
  I5V48_RS02905 (I5V48_02905) - 589523..590674 (+) 1152 WP_043026137.1 replication initiation/membrane attachment protein -
  I5V48_RS02910 (I5V48_02910) dnaI 590674..591573 (+) 900 WP_043026135.1 primosomal protein DnaI -
  I5V48_RS02915 (I5V48_02915) - 591570..592283 (+) 714 WP_043026134.1 NADPH-dependent oxidoreductase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26256.08 Da        Isoelectric Point: 5.0256

>NTDB_id=509509 I5V48_RS02890 WP_197315109.1 587064..587753(+) (covR) [Streptococcus suis strain YZDH1]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGEEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=509509 I5V48_RS02890 WP_197315109.1 587064..587753(+) (covR) [Streptococcus suis strain YZDH1]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGGAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTGGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCAACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T1LB30

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432