Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   I5044_RS02450 Genome accession   NZ_CP065354
Coordinates   526345..526914 (+) Length   189 a.a.
NCBI ID   WP_000872876.1    Uniprot ID   -
Organism   Staphylococcus aureus strain JW_comp_novo     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 521345..531914
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I5044_RS02425 (I5044_02425) cysE 522558..523205 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  I5044_RS02430 (I5044_02430) cysS 523189..524589 (+) 1401 WP_029753826.1 cysteine--tRNA ligase -
  I5044_RS02435 (I5044_02435) - 524582..524986 (+) 405 WP_000370186.1 Mini-ribonuclease 3 -
  I5044_RS02440 (I5044_02440) rlmB 524994..525740 (+) 747 WP_000390331.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  I5044_RS02445 (I5044_02445) - 525740..526264 (+) 525 WP_000664738.1 NYN domain-containing protein -
  I5044_RS02450 (I5044_02450) sigH 526345..526914 (+) 570 WP_000872876.1 sigma-70 family RNA polymerase sigma factor Regulator
  I5044_RS02455 (I5044_02455) rpmG 527029..527172 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  I5044_RS02460 (I5044_02460) secE 527228..527410 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  I5044_RS02465 (I5044_02465) nusG 527423..527971 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  I5044_RS02470 (I5044_02470) rplK 528152..528574 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  I5044_RS02475 (I5044_02475) rplA 528782..529474 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  I5044_RS02480 (I5044_02480) rplJ 529746..530246 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  I5044_RS02485 (I5044_02485) rplL 530289..530657 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  I5044_RS02490 (I5044_02490) - 530832..531440 (+) 609 WP_000020299.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.96 Da        Isoelectric Point: 9.6015

>NTDB_id=508732 I5044_RS02450 WP_000872876.1 526345..526914(+) (sigH) [Staphylococcus aureus strain JW_comp_novo]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=508732 I5044_RS02450 WP_000872876.1 526345..526914(+) (sigH) [Staphylococcus aureus strain JW_comp_novo]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAACAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAGCGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

99.471

100

0.995
  sigH Staphylococcus aureus N315

98.413

100

0.984