Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   I5043_RS02445 Genome accession   NZ_CP065353
Coordinates   530421..530990 (+) Length   189 a.a.
NCBI ID   WP_000872875.1    Uniprot ID   -
Organism   Staphylococcus aureus strain AR39_O1_merpol     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 525421..535990
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I5043_RS02420 (I5043_02420) cysE 526634..527281 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  I5043_RS02425 (I5043_02425) cysS 527265..528665 (+) 1401 WP_000631972.1 cysteine--tRNA ligase -
  I5043_RS02430 (I5043_02430) - 528658..529062 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  I5043_RS02435 (I5043_02435) rlmB 529070..529816 (+) 747 WP_000390334.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  I5043_RS02440 (I5043_02440) - 529816..530340 (+) 525 WP_000664738.1 NYN domain-containing protein -
  I5043_RS02445 (I5043_02445) sigH 530421..530990 (+) 570 WP_000872875.1 sigma-70 family RNA polymerase sigma factor Regulator
  I5043_RS02450 (I5043_02450) rpmG 531105..531248 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  I5043_RS02455 (I5043_02455) secE 531304..531486 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  I5043_RS02460 (I5043_02460) nusG 531499..532047 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  I5043_RS02465 (I5043_02465) rplK 532228..532650 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  I5043_RS02470 (I5043_02470) rplA 532858..533550 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  I5043_RS02475 (I5043_02475) rplJ 533822..534322 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  I5043_RS02480 (I5043_02480) rplL 534365..534733 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  I5043_RS02485 (I5043_02485) - 534908..535516 (+) 609 WP_000020308.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23079.92 Da        Isoelectric Point: 9.6015

>NTDB_id=508690 I5043_RS02445 WP_000872875.1 530421..530990(+) (sigH) [Staphylococcus aureus strain AR39_O1_merpol]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKII

Nucleotide


Download         Length: 570 bp        

>NTDB_id=508690 I5043_RS02445 WP_000872875.1 530421..530990(+) (sigH) [Staphylococcus aureus strain AR39_O1_merpol]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGGAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCTATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATAATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979