Detailed information
Bioinformatically predicted
Overview
| Name | comM | Type | Regulator |
| Locus tag | MYY_RS09655 | Genome accession | NC_017769 |
| Coordinates | 1821132..1821752 (-) | Length | 206 a.a. |
| NCBI ID | WP_000839909.1 | Uniprot ID | A0A098Z2X2 |
| Organism | Streptococcus pneumoniae ST556 | ||
| Function | fratricide immunity (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1809587..1850657 | 1821132..1821752 | within | 0 |
Gene organization within MGE regions
Location: 1809587..1850657
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MYY_RS09585 (MYY_1840) | - | 1809884..1810435 (-) | 552 | WP_001111247.1 | hypothetical protein | - |
| MYY_RS09590 (MYY_1841) | - | 1810425..1810622 (-) | 198 | WP_000890144.1 | hypothetical protein | - |
| MYY_RS09595 (MYY_1842) | - | 1810626..1811420 (-) | 795 | WP_001101215.1 | hypothetical protein | - |
| MYY_RS09600 (MYY_03390) | - | 1811828..1812253 (-) | 426 | WP_000204068.1 | hypothetical protein | - |
| MYY_RS09605 (MYY_1844) | - | 1812382..1812741 (-) | 360 | WP_000749821.1 | ImmA/IrrE family metallo-endopeptidase | - |
| MYY_RS09610 (MYY_03395) | - | 1812787..1812993 (-) | 207 | WP_000366087.1 | hypothetical protein | - |
| MYY_RS09615 (MYY_1845) | - | 1812980..1813141 (-) | 162 | WP_000289348.1 | helix-turn-helix domain-containing protein | - |
| MYY_RS09620 (MYY_1846) | lytA | 1813500..1814456 (-) | 957 | WP_000405240.1 | N-acetylmuramoyl-L-alanine amidase LytA | - |
| MYY_RS09625 (MYY_1847) | - | 1814832..1816202 (-) | 1371 | WP_001036271.1 | MATE family efflux transporter | - |
| MYY_RS09630 (MYY_1848) | recA | 1816509..1817675 (-) | 1167 | WP_001085462.1 | recombinase RecA | Machinery gene |
| MYY_RS09635 (MYY_1849) | cinA | 1817730..1818986 (-) | 1257 | WP_000642704.1 | competence/damage-inducible protein A | Machinery gene |
| MYY_RS09640 (MYY_1850) | brpA | 1819071..1820087 (-) | 1017 | WP_000239279.1 | biofilm formation/cell division transcriptional regulator BrpA | - |
| MYY_RS09645 (MYY_1851) | - | 1820095..1820613 (-) | 519 | WP_000455536.1 | GNAT family N-acetyltransferase | - |
| MYY_RS09650 (MYY_1852) | tsaE | 1820603..1821046 (-) | 444 | WP_000288230.1 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE | - |
| MYY_RS09655 (MYY_1853) | comM | 1821132..1821752 (-) | 621 | WP_000839909.1 | hypothetical protein | Regulator |
| MYY_RS09660 (MYY_1854) | - | 1822058..1822921 (-) | 864 | WP_001093609.1 | helix-turn-helix domain-containing protein | - |
| MYY_RS13565 (MYY_1855) | - | 1823113..1823283 (+) | 171 | WP_001227863.1 | PhrA family quorum-sensing system peptide | - |
| MYY_RS09670 (MYY_1856) | - | 1823685..1823999 (+) | 315 | WP_000420682.1 | YdcP family protein | - |
| MYY_RS09675 (MYY_1857) | - | 1824015..1824401 (+) | 387 | WP_000985015.1 | YdcP family protein | - |
| MYY_RS09680 (MYY_1858) | - | 1824430..1825815 (+) | 1386 | WP_000813488.1 | FtsK/SpoIIIE domain-containing protein | - |
| MYY_RS12400 | - | 1825818..1825970 (+) | 153 | WP_000879507.1 | hypothetical protein | - |
| MYY_RS09685 (MYY_1859) | mobT | 1825993..1827198 (+) | 1206 | WP_000398284.1 | MobT family relaxase | - |
| MYY_RS09690 (MYY_03400) | - | 1827241..1827462 (+) | 222 | WP_001009056.1 | hypothetical protein | - |
| MYY_RS09695 (MYY_1861) | - | 1827579..1828076 (+) | 498 | WP_000342539.1 | antirestriction protein ArdA | - |
| MYY_RS09700 (MYY_03405) | - | 1828165..1828557 (+) | 393 | WP_000723888.1 | conjugal transfer protein | - |
| MYY_RS09705 (MYY_1863) | - | 1828541..1830988 (+) | 2448 | WP_000331160.1 | ATP-binding protein | - |
| MYY_RS09710 (MYY_1864) | - | 1830991..1833168 (+) | 2178 | WP_001814875.1 | CD3337/EF1877 family mobilome membrane protein | - |
| MYY_RS09715 (MYY_1865) | - | 1833165..1834166 (+) | 1002 | WP_000769868.1 | lysozyme family protein | - |
| MYY_RS09720 (MYY_1866) | - | 1834163..1835095 (+) | 933 | WP_001224318.1 | conjugal transfer protein | - |
| MYY_RS13755 | - | 1835409..1835456 (+) | 48 | Protein_1858 | hypothetical protein | - |
| MYY_RS09725 (MYY_1867) | tet(M) | 1835472..1837391 (+) | 1920 | WP_000691729.1 | tetracycline resistance ribosomal protection protein Tet(M) | - |
| MYY_RS09735 (MYY_1868) | - | 1837755..1838000 (+) | 246 | WP_001813542.1 | hypothetical protein | - |
| MYY_RS09740 (MYY_1869) | - | 1837997..1838332 (+) | 336 | WP_000806926.1 | hypothetical protein | - |
| MYY_RS09745 (MYY_1870) | - | 1838345..1838713 (+) | 369 | WP_000567222.1 | hypothetical protein | - |
| MYY_RS09750 (MYY_1871) | - | 1838700..1838999 (+) | 300 | WP_001072467.1 | DUF5960 family protein | - |
| MYY_RS09755 (MYY_1872) | msr(D) | 1839117..1840580 (-) | 1464 | WP_000420313.1 | ABC-F type ribosomal protection protein Msr(D) | - |
| MYY_RS09760 (MYY_1873) | mef(A) | 1840700..1841917 (-) | 1218 | WP_000417519.1 | macrolide efflux MFS transporter Mef(A) | - |
| MYY_RS09765 (MYY_1874) | - | 1842303..1842473 (-) | 171 | WP_000873143.1 | hypothetical protein | - |
| MYY_RS12410 (MYY_03420) | - | 1842995..1843186 (+) | 192 | WP_001860868.1 | cysteine-rich KTR domain-containing protein | - |
| MYY_RS09770 (MYY_1875) | - | 1843246..1843599 (-) | 354 | WP_001227347.1 | helix-turn-helix transcriptional regulator | - |
| MYY_RS09775 (MYY_1876) | - | 1844104..1844526 (+) | 423 | WP_000804885.1 | sigma-70 family RNA polymerase sigma factor | - |
| MYY_RS09780 (MYY_03425) | - | 1844523..1844753 (+) | 231 | WP_000857133.1 | helix-turn-helix domain-containing protein | - |
| MYY_RS13425 | - | 1844979..1845230 (-) | 252 | WP_001845478.1 | hypothetical protein | - |
| MYY_RS09785 (MYY_1877) | - | 1845214..1845417 (+) | 204 | WP_000814511.1 | excisionase | - |
| MYY_RS09790 (MYY_1878) | - | 1845499..1846716 (+) | 1218 | WP_001291561.1 | tyrosine-type recombinase/integrase | - |
| MYY_RS09795 (MYY_1880) | - | 1847607..1849622 (+) | 2016 | WP_000732395.1 | DUF1430 domain-containing protein | - |
| MYY_RS09800 (MYY_1881) | - | 1849624..1850256 (+) | 633 | WP_000571425.1 | ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 206 a.a. Molecular weight: 23540.66 Da Isoelectric Point: 10.1254
>NTDB_id=50842 MYY_RS09655 WP_000839909.1 1821132..1821752(-) (comM) [Streptococcus pneumoniae ST556]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF
Nucleotide
Download Length: 621 bp
>NTDB_id=50842 MYY_RS09655 WP_000839909.1 1821132..1821752(-) (comM) [Streptococcus pneumoniae ST556]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATACTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATACTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comM | Streptococcus pneumoniae D39 |
99.515 |
100 |
0.995 |
| comM | Streptococcus pneumoniae R6 |
99.515 |
100 |
0.995 |
| comM | Streptococcus pneumoniae TIGR4 |
99.515 |
100 |
0.995 |
| comM | Streptococcus mitis NCTC 12261 |
38.462 |
94.66 |
0.364 |
| comM | Streptococcus mitis SK321 |
38.462 |
94.66 |
0.364 |