Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   I2438_RS08355 Genome accession   NZ_CP065190
Coordinates   1693090..1694412 (-) Length   440 a.a.
NCBI ID   WP_021321063.1    Uniprot ID   A0AAW3GKF3
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ36     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1688090..1699412
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2438_RS08345 (HCFMJIKG_01659) hpf 1691826..1692374 (-) 549 WP_012516134.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  I2438_RS08350 (HCFMJIKG_01660) - 1692450..1693115 (-) 666 WP_021321062.1 ComF family protein -
  I2438_RS08355 (HCFMJIKG_01661) comFA/cflA 1693090..1694412 (-) 1323 WP_021321063.1 DEAD/DEAH box helicase Machinery gene
  I2438_RS08360 (HCFMJIKG_01662) - 1694468..1695109 (+) 642 WP_021321064.1 YigZ family protein -
  I2438_RS08365 (HCFMJIKG_01663) cysK 1695231..1696157 (+) 927 WP_012516138.1 cysteine synthase A -
  I2438_RS08370 (HCFMJIKG_01664) - 1696544..1696906 (-) 363 WP_012516140.1 S1 RNA-binding domain-containing protein -
  I2438_RS08375 (HCFMJIKG_01665) - 1696906..1698306 (-) 1401 WP_021321065.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  I2438_RS08380 (HCFMJIKG_01666) - 1698340..1698981 (-) 642 WP_021321066.1 response regulator -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 49893.06 Da        Isoelectric Point: 9.6896

>NTDB_id=507780 I2438_RS08355 WP_021321063.1 1693090..1694412(-) (comFA/cflA) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
MENIENYYGRLLPEGQCPKAVSVWACSLQSMIAKKGTLYCQRCSSLIEKAHQLPSGAYYCRACLVFGRNQSDRPLLYFPP
ASFPKGHYLRWQGQLTTYQAAISHQLTNHVKLKQDTLVHAVTGAGKTEMMYEAIAAVVNKGGWVCIASPRVDVCIELEKR
LSRDFSCQICLMHAESEVYHRSPIIVATTHQLMTFYHAFDLLIIDEVDAFPFVNNRQLNHAAHQAAKADAVTVYLTATST
KDLERKVKQKELVKLTLARRFHGKPLVVPKYQRLFSLLEAINRGKLPRRLITLVKKQRATGYPLLIFFPLIELAEQCCQL
LQKYFPKETIAHASSQSSNRMTIIEQFRQGQITILISTTILERGVTFPTIDVFVLLANHRLYTSSSLIQISGRVGRSLER
PEGQVLFFHDGISKAMLKAVREIKDMNQKGYQNELSTLSQ

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=507780 I2438_RS08355 WP_021321063.1 1693090..1694412(-) (comFA/cflA) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
ATGGAGAATATCGAAAATTACTATGGACGTCTTTTACCCGAAGGGCAATGCCCAAAGGCTGTTTCTGTCTGGGCTTGCAG
CTTACAAAGCATGATCGCTAAAAAAGGAACATTATACTGCCAACGCTGTAGCAGCTTAATTGAGAAAGCTCATCAGCTAC
CTAGCGGTGCTTACTATTGTAGAGCCTGTCTCGTTTTTGGTCGAAACCAATCTGATCGCCCCTTGCTCTATTTTCCACCG
GCTTCTTTTCCAAAGGGACATTATCTGAGGTGGCAAGGACAGCTCACGACATATCAGGCAGCTATCTCTCATCAGCTTAC
TAACCATGTTAAGCTCAAGCAAGACACCTTAGTTCATGCGGTTACTGGTGCTGGCAAAACAGAGATGATGTATGAAGCTA
TTGCAGCAGTTGTTAATAAGGGTGGCTGGGTCTGCATTGCTAGTCCACGAGTTGATGTTTGCATAGAGCTTGAAAAACGA
CTATCGCGGGACTTTTCCTGTCAAATCTGCCTTATGCATGCTGAGTCAGAGGTTTATCATAGAAGCCCCATTATCGTTGC
CACAACACATCAATTGATGACCTTTTACCATGCTTTTGATCTGCTCATTATTGACGAAGTAGATGCCTTCCCCTTTGTCA
ATAATCGTCAATTAAACCATGCTGCTCATCAGGCTGCAAAAGCAGATGCAGTGACAGTATACCTAACAGCAACCTCTACA
AAAGACTTAGAGCGCAAGGTCAAGCAAAAAGAGCTTGTCAAATTGACATTGGCAAGAAGATTTCATGGCAAGCCCTTAGT
TGTTCCAAAGTATCAAAGATTATTCTCCCTTTTAGAGGCTATCAATCGCGGGAAATTGCCTAGAAGACTAATCACCCTAG
TCAAAAAACAAAGGGCAACTGGCTATCCTCTCTTAATCTTTTTTCCGCTTATTGAGCTAGCTGAGCAATGCTGTCAGCTG
CTCCAAAAGTATTTTCCTAAGGAAACTATTGCCCATGCTTCCAGTCAGTCATCAAATCGAATGACTATCATTGAGCAATT
CAGACAAGGACAAATCACTATACTTATATCAACAACCATTTTGGAAAGAGGTGTGACCTTTCCGACCATAGATGTCTTTG
TCTTATTAGCCAATCATCGCCTTTACACAAGCAGCAGTCTTATTCAGATTTCAGGTCGCGTCGGGCGTTCCTTGGAAAGG
CCTGAAGGACAGGTGCTGTTTTTTCATGATGGCATTAGCAAGGCCATGCTCAAGGCAGTGCGGGAGATAAAGGATATGAA
TCAAAAAGGGTATCAAAATGAACTGTCTACTCTGTCACAATAA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(101-244)

Helicase conserved C-terminal domain (Helicase_C)

(287-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis SK321

52.941

96.591

0.511
  comFA/cflA Streptococcus pneumoniae D39

52.941

96.591

0.511
  comFA/cflA Streptococcus pneumoniae R6

52.941

96.591

0.511
  comFA/cflA Streptococcus pneumoniae Rx1

52.941

96.591

0.511
  comFA/cflA Streptococcus pneumoniae TIGR4

52.941

96.591

0.511
  comFA/cflA Streptococcus mitis NCTC 12261

52.706

96.591

0.509
  comFA Lactococcus lactis subsp. cremoris KW2

48.724

89.091

0.434