Detailed information NTG0050686

Bioinformatically predicted

Overview

• Name: lytF
• Type: Regulator
• Locus tag: SANR_RS00260
• Genome accession: NC_022239
• Coordinates: 40701..42635 (-)
• Length: 644 a.a.
• NCBI ID: WP_003036896.1
• Uniprot ID: I0SBZ9
• Organism: Streptococcus anginosus C238
• Function: cell lysis (predicted from homology) Cell lysis

Genomic Context

Location: 35701..47635

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SANR_RS00240 (SANR_0049)	purM	37282..38301 (+)	1020	WP_020999419.1	phosphoribosylformylglycinamidine cyclo-ligase	-
SANR_RS00245 (SANR_0050)	purN	38301..38855 (+)	555	WP_020999420.1	phosphoribosylglycinamide formyltransferase	-
SANR_RS00250	-	38913..39080 (+)	168	WP_003036929.1	hypothetical protein	-
SANR_RS00255 (SANR_0051)	purH	39095..40642 (+)	1548	WP_003036901.1	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	-
SANR_RS00260 (SANR_0052)	lytF	40701..42635 (-)	1935	WP_003036896.1	GBS Bsp-like repeat-containing protein	Regulator
SANR_RS00265 (SANR_0053)	purD	42830..44095 (+)	1266	WP_003036964.1	phosphoribosylamine--glycine ligase	-
SANR_RS00270 (SANR_0054)	-	44085..44519 (+)	435	WP_020999421.1	DUF523 domain-containing protein	-
SANR_RS00275 (SANR_0055)	purE	44757..45245 (+)	489	WP_003037056.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
SANR_RS00280 (SANR_0056)	purK	45232..46320 (+)	1089	WP_020999422.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
SANR_RS00285 (SANR_0057)	-	46330..46557 (+)	228	WP_003036973.1	hypothetical protein	-
SANR_RS00290 (SANR_0058)	-	46568..47530 (+)	963	WP_003036988.1	hypothetical protein	-

Sequence

Protein

• Length: 644 a.a.
• Molecular weight: 71159.00 Da
• Isoelectric Point: 8.5273

>NTDB_id=50686 SANR_RS00260 WP_003036896.1 40701..42635(-) (lytF) [Streptococcus anginosus C238]
MKKYSQLFLLSSTILGIFSAQLTAQASEADNAQKSSNPAILASNITVNVSGNTASINYTRSQTQVPYTIYHAVWSDENGQ
DDIKWYSAPQTPTTAIDLRQHTGYGTFHVHTYININGKMVGLNGTTFKVEKPASGTVSTTVLGKTAQISFTRNKDQTNAN
ILHAVWSDEKGQDDIKWYTAGQDTTEIDLSNHKGYGVYHVHTYESKNGKMIGLNGTTFNLEKPNPTIQTSFPEPGIMDIQ
IKNVPKTIYKLTVPAWSDRNEQDDLQWYAATKNPDGSYNVRVELKKHNYDTGTYHIHLYGESYVKPEFTGLAGITAQVDA
DKLPSEEEQKPFFSVENINQEQGTYTVKVSETSKSKPIQSVRVPIWSTSNQSNIKWYAATNHGDGTFTAAFDIRNHQVLS
GTYTNHIYVKYKDGSEHSYVTDSVAMSAEKIKTKVSVAKRSTYLYEVTVTDAYGDGKISLPTWSEVNGQDDIQWYTATKA
GNGIYKFTIDTQKHTGSGLFHTHVYRNLNGQMIGLTGTSYQVEKPAISFQPNYAAATTYPKGQCTWGAKALAPWAGNYWG
NGGDWAASARRAGFKTGTTPQVGAIICWTDGGYGHVGVVTHVASNTRIQIQEANYAGKQYIGNFRGWFNPHAAGQGAVSY
IYPK

Nucleotide

• Length: 1935 bp

>NTDB_id=50686 SANR_RS00260 WP_003036896.1 40701..42635(-) (lytF) [Streptococcus anginosus C238]
ATGAAGAAATACAGTCAATTATTTTTACTATCTAGCACTATTTTGGGCATTTTTTCTGCTCAACTAACTGCTCAAGCCTC
GGAAGCAGATAATGCTCAAAAAAGCTCAAATCCAGCAATTCTTGCTAGCAACATTACCGTCAATGTTTCTGGAAATACAG
CTTCTATTAACTACACACGCTCACAGACACAAGTTCCTTACACCATTTACCACGCTGTTTGGTCTGATGAAAATGGGCAA
GACGATATCAAATGGTATTCTGCGCCTCAGACACCAACTACAGCTATTGATTTGCGTCAGCACACTGGTTATGGAACCTT
TCATGTTCACACTTATATCAATATCAATGGAAAAATGGTTGGTTTAAACGGAACGACTTTCAAAGTAGAAAAACCAGCTA
GCGGCACGGTTTCTACAACCGTTTTAGGAAAGACTGCTCAAATATCCTTTACTCGAAACAAAGATCAAACAAATGCCAAT
ATTTTACACGCTGTTTGGTCTGACGAAAAAGGACAAGATGACATCAAGTGGTATACGGCAGGGCAAGACACAACAGAAAT
TGACTTATCCAATCATAAAGGATACGGTGTTTACCATGTTCATACTTATGAAAGTAAAAACGGAAAGATGATTGGATTAA
ATGGCACCACTTTTAACCTTGAAAAACCAAATCCTACTATTCAGACTAGCTTCCCTGAGCCTGGTATCATGGATATTCAG
ATCAAAAATGTTCCTAAAACAATCTACAAACTAACTGTTCCGGCTTGGTCTGACCGCAACGAACAGGATGATCTTCAATG
GTATGCAGCTACTAAAAATCCTGATGGAAGCTACAATGTTAGAGTTGAGCTAAAAAAACACAACTATGACACAGGAACTT
ATCACATTCATCTTTACGGAGAAAGCTATGTCAAACCAGAGTTTACTGGCTTAGCTGGAATCACTGCCCAAGTTGATGCT
GATAAATTGCCTTCTGAAGAAGAGCAAAAACCATTCTTCTCTGTTGAAAATATCAATCAAGAACAAGGGACTTATACCGT
CAAAGTTAGTGAAACTTCAAAGTCCAAGCCGATTCAATCCGTCCGAGTACCTATTTGGAGCACGAGCAATCAAAGCAATA
TCAAGTGGTATGCAGCCACTAATCACGGTGACGGAACATTTACGGCAGCATTTGATATTCGCAATCATCAAGTTTTGTCT
GGAACATATACCAATCATATTTATGTGAAATATAAAGACGGTAGCGAGCATAGTTACGTAACGGATTCGGTTGCTATGTC
CGCAGAAAAAATTAAAACCAAGGTATCTGTCGCTAAACGCTCAACTTATCTTTATGAGGTGACAGTGACAGATGCTTACG
GCGATGGCAAGATTAGCCTACCGACTTGGTCTGAAGTCAACGGCCAAGATGATATTCAGTGGTACACCGCTACTAAAGCT
GGAAATGGAATTTACAAATTCACAATTGATACGCAAAAACACACTGGCAGCGGGCTTTTCCATACACATGTCTACCGCAA
TCTCAACGGTCAAATGATTGGACTAACAGGTACGAGCTATCAAGTAGAGAAACCTGCTATCTCTTTCCAACCAAATTATG
CCGCAGCAACGACTTATCCAAAAGGGCAATGCACTTGGGGCGCCAAAGCTCTTGCACCTTGGGCTGGCAATTACTGGGGC
AATGGTGGTGATTGGGCTGCTAGCGCCAGACGAGCTGGTTTTAAAACCGGTACAACTCCACAAGTAGGGGCTATTATTTG
TTGGACAGACGGTGGTTACGGTCACGTTGGAGTTGTTACTCACGTTGCCTCAAACACACGCATTCAGATTCAAGAGGCCA
ACTACGCTGGAAAACAGTATATTGGCAACTTCCGCGGCTGGTTCAATCCTCATGCAGCTGGACAAGGAGCAGTTAGTTAC
ATTTATCCAAAATAA

Domains

Predicted by InterProScan.

• GBS Bsp-like repeat (GBS_Bsp-like) (437-518)

• GBS Bsp-like repeat (GBS_Bsp-like) (335-419)

• GBS Bsp-like repeat (GBS_Bsp-like) (151-218)

• GBS Bsp-like repeat (GBS_Bsp-like) (67-126)

• GBS Bsp-like repeat (GBS_Bsp-like) (232-302)

• CHAP domain (CHAP) (537-614)

3D structure

• AlphaFold DB: I0SBZ9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
lytF	Streptococcus gordonii strain NCTC7865	46.36	81.056	0.376
lytF	Streptococcus gordonii str. Challis substr. CH1	45.155	80.124	0.362