Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   I2436_RS07605 Genome accession   NZ_CP065060
Coordinates   1621272..1622594 (-) Length   440 a.a.
NCBI ID   WP_021321063.1    Uniprot ID   A0AAW3GKF3
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ28     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1616272..1627594
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2436_RS07595 (GDAKBCAL_01524) raiA 1620008..1620556 (-) 549 WP_012516134.1 ribosome-associated translation inhibitor RaiA -
  I2436_RS07600 (GDAKBCAL_01525) - 1620632..1621213 (-) 582 WP_231197032.1 ComF family protein -
  I2436_RS07605 (GDAKBCAL_01526) comFA/cflA 1621272..1622594 (-) 1323 WP_021321063.1 helicase-related protein Machinery gene
  I2436_RS07610 (GDAKBCAL_01527) - 1622650..1623291 (+) 642 WP_021321064.1 YigZ family protein -
  I2436_RS07615 (GDAKBCAL_01528) cysK 1623413..1624339 (+) 927 WP_012516138.1 cysteine synthase A -
  I2436_RS07620 (GDAKBCAL_01529) - 1624740..1625102 (-) 363 WP_014623356.1 S1 RNA-binding domain-containing protein -
  I2436_RS07625 (GDAKBCAL_01530) - 1625102..1626502 (-) 1401 WP_206152756.1 Cof-type HAD-IIB family hydrolase -
  I2436_RS07630 (GDAKBCAL_01531) - 1626535..1627176 (-) 642 WP_041785672.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 49893.06 Da        Isoelectric Point: 9.6896

>NTDB_id=506557 I2436_RS07605 WP_021321063.1 1621272..1622594(-) (comFA/cflA) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
MENIENYYGRLLPEGQCPKAVSVWACSLQSMIAKKGTLYCQRCSSLIEKAHQLPSGAYYCRACLVFGRNQSDRPLLYFPP
ASFPKGHYLRWQGQLTTYQAAISHQLTNHVKLKQDTLVHAVTGAGKTEMMYEAIAAVVNKGGWVCIASPRVDVCIELEKR
LSRDFSCQICLMHAESEVYHRSPIIVATTHQLMTFYHAFDLLIIDEVDAFPFVNNRQLNHAAHQAAKADAVTVYLTATST
KDLERKVKQKELVKLTLARRFHGKPLVVPKYQRLFSLLEAINRGKLPRRLITLVKKQRATGYPLLIFFPLIELAEQCCQL
LQKYFPKETIAHASSQSSNRMTIIEQFRQGQITILISTTILERGVTFPTIDVFVLLANHRLYTSSSLIQISGRVGRSLER
PEGQVLFFHDGISKAMLKAVREIKDMNQKGYQNELSTLSQ

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=506557 I2436_RS07605 WP_021321063.1 1621272..1622594(-) (comFA/cflA) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
ATGGAGAATATCGAAAATTACTATGGACGTCTTTTACCCGAAGGGCAATGCCCAAAGGCTGTTTCTGTCTGGGCTTGCAG
CTTACAAAGCATGATCGCTAAAAAAGGAACATTATACTGCCAACGCTGTAGCAGCTTAATTGAGAAAGCTCATCAGCTAC
CTAGCGGTGCTTACTATTGTAGAGCCTGTCTCGTTTTTGGTCGAAACCAATCTGATCGCCCCTTGCTCTATTTTCCACCG
GCTTCTTTTCCAAAGGGACATTATCTGAGGTGGCAAGGACAGCTCACGACATATCAGGCAGCTATCTCTCATCAGCTTAC
TAACCATGTTAAGCTCAAGCAAGACACCTTAGTTCATGCGGTTACTGGTGCTGGCAAAACAGAGATGATGTATGAAGCTA
TTGCAGCAGTTGTTAATAAGGGTGGCTGGGTCTGCATTGCTAGTCCACGAGTTGATGTTTGCATAGAGCTTGAAAAACGA
CTATCGCGGGACTTTTCCTGTCAAATCTGCCTTATGCATGCTGAGTCAGAGGTTTATCATAGAAGCCCCATTATCGTTGC
CACAACACATCAATTGATGACCTTTTACCATGCTTTTGATCTGCTCATTATTGACGAAGTAGATGCCTTCCCCTTTGTCA
ATAATCGTCAATTAAACCATGCTGCTCATCAGGCTGCAAAAGCAGATGCAGTGACAGTATACCTAACAGCAACCTCTACA
AAAGACTTAGAGCGCAAGGTCAAGCAAAAAGAGCTTGTCAAATTGACATTGGCAAGAAGATTTCATGGCAAGCCCTTAGT
TGTTCCAAAGTATCAAAGATTATTCTCCCTTTTAGAGGCTATCAATCGCGGGAAATTGCCTAGAAGACTAATCACCCTAG
TCAAAAAACAAAGGGCAACTGGCTATCCTCTCTTAATCTTTTTTCCGCTTATTGAGCTAGCTGAGCAATGCTGTCAGCTG
CTCCAAAAGTATTTTCCTAAGGAAACTATTGCCCATGCTTCCAGTCAGTCATCAAATCGAATGACTATCATTGAGCAATT
CAGACAAGGACAAATCACTATACTTATATCAACAACCATTTTGGAAAGAGGTGTGACCTTTCCGACCATAGATGTCTTTG
TCTTATTAGCCAATCATCGCCTTTACACAAGCAGCAGTCTTATTCAGATTTCAGGTCGCGTCGGGCGTTCCTTGGAAAGG
CCTGAAGGACAGGTGCTGTTTTTTCATGATGGCATTAGCAAGGCCATGCTCAAGGCAGTGCGGGAGATAAAGGATATGAA
TCAAAAAGGGTATCAAAATGAACTGTCTACTCTGTCACAATAA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(101-244)

Helicase conserved C-terminal domain (Helicase_C)

(287-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis SK321

52.941

96.591

0.511
  comFA/cflA Streptococcus pneumoniae D39

52.941

96.591

0.511
  comFA/cflA Streptococcus pneumoniae R6

52.941

96.591

0.511
  comFA/cflA Streptococcus pneumoniae Rx1

52.941

96.591

0.511
  comFA/cflA Streptococcus pneumoniae TIGR4

52.941

96.591

0.511
  comFA/cflA Streptococcus mitis NCTC 12261

52.706

96.591

0.509
  comFA Lactococcus lactis subsp. cremoris KW2

48.724

89.091

0.434