Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   I2434_RS05295 Genome accession   NZ_CP065058
Coordinates   1122993..1124222 (-) Length   409 a.a.
NCBI ID   WP_043053130.1    Uniprot ID   A0A7Z8ZVZ1
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ18     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1117993..1129222
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2434_RS05280 (MCPGFBBE_01050) - 1120678..1120965 (-) 288 WP_206157565.1 hypothetical protein -
  I2434_RS05285 (MCPGFBBE_01051) - 1120991..1122247 (-) 1257 WP_206157566.1 ISL3 family transposase -
  I2434_RS05290 (MCPGFBBE_01052) yihA 1122384..1122983 (-) 600 WP_012677890.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  I2434_RS05295 (MCPGFBBE_01053) clpX 1122993..1124222 (-) 1230 WP_043053130.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  I2434_RS05300 (MCPGFBBE_01054) - 1124258..1124428 (-) 171 WP_012515696.1 hypothetical protein -
  I2434_RS05305 (MCPGFBBE_01055) - 1124448..1124945 (-) 498 WP_165619333.1 dihydrofolate reductase -
  I2434_RS05310 (MCPGFBBE_01056) - 1125026..1125865 (-) 840 WP_043029774.1 thymidylate synthase -
  I2434_RS05315 (MCPGFBBE_01057) - 1126050..1127228 (+) 1179 WP_115266873.1 hydroxymethylglutaryl-CoA synthase -
  I2434_RS05320 (MCPGFBBE_01058) - 1127215..1128498 (+) 1284 WP_206157689.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45157.67 Da        Isoelectric Point: 4.5698

>NTDB_id=506427 I2434_RS05295 WP_043053130.1 1122993..1124222(-) (clpX) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDILNQYVIGQER
AKRALSVAVYNHYKRISFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKIDDNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRI
LTEPRNALVKQYQALLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVTKVRITKEAVEG
QSKPVLEIA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=506427 I2434_RS05295 WP_043053130.1 1122993..1124222(-) (clpX) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
ATGGCAGGAAATCGTAGTAACGATATTAAGGTTCATTGCTCGTTTTGCGGCAAGAGCCAAGACGAAGTGAAAAAAATTAT
TGCAGGCAATAACGTCTTTATTTGTAACGAATGTGTTGCCTTATCACAAGAAATCATCAAGGAAGAATTGGCAGAAGAGG
TTCTCGCTGATCTGACTGAGGTACCAAAGCCAAAAGAGCTCCTTGATATTTTAAACCAATACGTCATTGGTCAGGAGCGT
GCTAAGAGAGCCTTATCAGTTGCAGTTTATAATCATTACAAGAGGATTTCATTTACTGAGAGTCGTGACGATGATGATGT
GGATTTGCAAAAGTCAAACATTCTGATGATTGGACCAACAGGCTCAGGAAAGACCTTTTTGGCACAGACCCTGGCTAAGA
GTCTGAATGTTCCGTTTGCTATTGCTGATGCAACCTCTTTGACTGAGGCAGGCTATGTCGGAGAAGATGTGGAAAATATC
CTTCTGAAATTAATTCAAGCCGCTGATTACAATGTTGAACGTGCAGAGCGTGGCATTATTTATGTTGATGAAATTGATAA
AATCGCTAAAAAAGGTGAGAATGTCTCTATCACTCGTGATGTATCAGGAGAGGGTGTCCAGCAAGCTTTGCTAAAAATCA
TTGAAGGAACGGTTGCCAGTGTTCCACCACAGGGTGGTCGTAAGCACCCAAACCAAGAGATGATACAGATTGATACCAAA
AATATCTTGTTTATCGTCGGAGGCGCTTTTGATGGTATCGAAGAAATTGTCAAGCAGCGCTTGGGAGAAAAGATCATTGG
CTTTGGGCAAAATAGTCGAAAGATTGATGACAATGCTTCCTATATGCAGGAGATCATTGCTGAGGATATTCAAAAATTTG
GTCTGATTCCCGAATTTATTGGACGCTTGCCTGTTGTGGCAGCGCTTGAGCAGCTTAATACTGAGGATTTGATTCGTATT
TTAACAGAGCCTAGAAATGCCCTTGTGAAGCAATATCAAGCCTTATTGTCATATGATGGCGTAGAGCTTGAGTTTGAAAA
GGGGGCTCTGGAGGCTATTGCAGGCAGGGCTATTGAGCGCAAGACTGGTGCGCGTGGTCTGAGGTCTATTATTGAAGAAA
CCATGCTGGATATCATGTTTGAGGTGCCAAGCCAAGAGGAAGTAACCAAGGTACGCATTACTAAGGAAGCTGTCGAGGGT
CAATCAAAGCCCGTTTTAGAGATAGCCTAG

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-390)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7Z8ZVZ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

88.753

100

0.888
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

59.102

98.044

0.579