Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   I2433_RS03345 Genome accession   NZ_CP065056
Coordinates   667401..668753 (+) Length   450 a.a.
NCBI ID   WP_014623188.1    Uniprot ID   A0A6M1KZW6
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ14     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 662401..673753
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2433_RS03320 (JDBNIEOD_00657) - 662524..663063 (+) 540 WP_043039174.1 hypothetical protein -
  I2433_RS03325 (JDBNIEOD_00658) - 663060..664175 (+) 1116 WP_043039173.1 acetyl-CoA C-acyltransferase -
  I2433_RS03330 (JDBNIEOD_00659) - 664165..665427 (+) 1263 WP_043039172.1 AMP-binding protein -
  I2433_RS03335 (JDBNIEOD_00660) - 665473..666489 (+) 1017 WP_111678244.1 DUF3114 domain-containing protein -
  I2433_RS03340 (JDBNIEOD_00661) vicR 666698..667408 (+) 711 WP_012677635.1 response regulator YycF Regulator
  I2433_RS03345 (JDBNIEOD_00662) vicK 667401..668753 (+) 1353 WP_014623188.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I2433_RS03350 (JDBNIEOD_00663) vicX 668757..669566 (+) 810 WP_021320992.1 MBL fold metallo-hydrolase Regulator
  I2433_RS03355 (JDBNIEOD_00664) - 669757..671499 (+) 1743 WP_206152432.1 restriction endonuclease FokI C-terminal domain-containing protein -
  I2433_RS03360 (JDBNIEOD_00665) - 671520..673451 (-) 1932 WP_042670951.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51527.91 Da        Isoelectric Point: 5.5557

>NTDB_id=506365 I2433_RS03345 WP_014623188.1 667401..668753(+) (vicK) [Streptococcus equi subsp. zooepidemicus strain SEZ14]
MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLMSHKIRDLINGRYTDTINEKADIELMELSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVTQLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITS
IWLEIDNDKMTQVIENILNNAIKYSPDGGKIVVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=506365 I2433_RS03345 WP_014623188.1 667401..668753(+) (vicK) [Streptococcus equi subsp. zooepidemicus strain SEZ14]
ATGACTAAGGACATCATTGGAAACCTTTCTGCATTTGAGCTAGCCATACTCTTATTGCTTGTTTTTGTTGCTTTTTATTT
CATTCATTTAGCCATTCGTGATTATCGCAATGCTCGGATCATTCGTCTGATGAGCCACAAGATAAGAGATTTGATCAATG
GTCGCTATACTGATACGATCAATGAAAAGGCTGATATTGAATTGATGGAGCTGTCTGAGCAGCTCAATGACCTATCAGAT
GTTTTTCGTCTGACTCATGAAAACCTTGCTCAAGAAAAAAATCGTCTTGCTAGTATTTTGGCTTATATGACAGATGGGGT
CCTTGCGACCAATCGTTCCGGCAAGATTATCATGATTAATGAGACTGCTCAAAAGCAGCTCAATTTAAATCGCGAGCAGG
CCTTGGAAAAAAACATTACAGATTTATTAGACAGTGACTCCCCTTATACCTACCGAGAGCTGGTCTCAAAAACACCGATT
GTGACCTTAAACCGTCGTAATGATACAGGAGAATTTGTTTCCCTGCGGCTGCGCTTTGCGCTTAATAGGCGAGAGAGCGG
CTTTATTTCAGGTCTGGTTGTTGTGCTTCATGACACGACTGAGCAGGAAAAGGAAGAGCGTGAGCGCAGACTCTTTGTTT
CAAATGTTAGCCATGAGCTGCGGACACCTTTGACCTCTGTCAAGTCATACCTAGAGGCTCTAGATGAGGGCGCGCTAAAG
GAGGACATCGCTCCAAGCTTTATAAAGGTCTCACTAGATGAAACCAATCGCATGATGCGCATGATTTCAGATTTGCTCAA
CCTATCAAGAATTGATAATCATGTGACACAGCTGTCTGTTGAAATGACCAACTTTACAGCCTTTATGACCTCTATCTTAA
ACCGCTTTGATTTGGTGAAAAATCAGCACACCAGTACAGGAAAATCCTATGAAATTGTCAGAGATTACCCTATCACCTCT
ATTTGGCTAGAAATTGACAATGACAAAATGACGCAGGTTATCGAAAATATTTTAAACAATGCAATCAAATATTCACCCGA
TGGCGGAAAAATTGTCGTCAACATGAAAACAACAGATACCCAGCTAATCATTTCGATTTCTGATGAGGGCTTGGGCATAC
CAAAGAAGGACCTGCCTTTGATTTTTGACCGTTTTTACCGAGTGGATAAGGCTAGAAGTCGGGCTCAAGGAGGAACTGGT
CTAGGCTTAGCGATTGCTAAAGAAATTATCAAGCAGCATCGAGGCTTTATTTGGGCCAAGAGCGATTATGGCAAGGGCTC
AACCTTTACCATTGTGTTACCTTACGAAAAGGATGCTGCTATCTATGATGAATGGGAGGATGATATTGATTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6M1KZW6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92

0.678
  micB Streptococcus pneumoniae Cp1015

66.824

94.444

0.631