Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   I6L88_RS03295 Genome accession   NZ_CP077404
Coordinates   657211..658998 (+) Length   595 a.a.
NCBI ID   WP_002263201.1    Uniprot ID   Q8CWX4
Organism   Streptococcus mutans strain FDAARGOS 1458     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 652211..663998
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L88_RS03270 (I6L88_03270) - 652289..652930 (+) 642 WP_002265582.1 DUF4352 domain-containing protein -
  I6L88_RS03275 (I6L88_03275) eno 653327..654625 (+) 1299 WP_002263196.1 surface-displayed alpha-enolase -
  I6L88_RS03280 (I6L88_03280) - 654689..654985 (+) 297 WP_002263197.1 TetR/AcrR family transcriptional regulator -
  I6L88_RS03285 (I6L88_03285) - 655199..655894 (+) 696 WP_002263871.1 YjjG family noncanonical pyrimidine nucleotidase -
  I6L88_RS03290 (I6L88_03290) - 655937..657093 (-) 1157 Protein_642 low temperature requirement protein A -
  I6L88_RS03295 (I6L88_03295) uvrC 657211..658998 (+) 1788 WP_002263201.1 excinuclease ABC subunit UvrC Machinery gene
  I6L88_RS03300 (I6L88_03300) - 659145..659747 (+) 603 WP_002268287.1 nitroreductase family protein -
  I6L88_RS03305 (I6L88_03305) pepV 659762..661168 (+) 1407 WP_002279977.1 dipeptidase PepV -
  I6L88_RS03310 (I6L88_03310) - 661241..661828 (+) 588 WP_002263204.1 uracil-DNA glycosylase family protein -
  I6L88_RS03315 (I6L88_03315) - 661956..662258 (-) 303 WP_002263205.1 helix-turn-helix transcriptional regulator -
  I6L88_RS03320 (I6L88_03320) - 662349..662699 (+) 351 WP_002263206.1 nuclear transport factor 2 family protein -
  I6L88_RS03325 (I6L88_03325) - 662717..663520 (+) 804 WP_002264095.1 amidohydrolase family protein -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68892.29 Da        Isoelectric Point: 9.4536

>NTDB_id=506191 I6L88_RS03295 WP_002263201.1 657211..658998(+) (uvrC) [Streptococcus mutans strain FDAARGOS 1458]
MNELIKHKLELLPDSPGCYIHKDKNGTIIYVGKAKNLKNRVRSYFHGSHNTKTELLVSEIEDFEYIVTGSNTEALLLEIN
LIQENKPKYNIRLKDDKSYPFIKITNEPYPRLLITRQVKKDGGLYFGPYPDSGAATEIKRLLDRLFPFKKCTNPANKVCF
YYHLGQCKAHTICQTDQTYWDSLKEDVKNFLNGRDDKIVNELRDKMTKASELMEFERAAEYRDLIEGIGLLRTKQRVMNQ
DMQDRDIFGYYVDKGWMCVQVFFIRQGKLIQRDVNMFPYYNESEEDFLTYVGQFYQDNRHFIPKEIFIPRNIDETLVKAV
VNTKIIKPQRGEKKQLVNLATKNARVSLQQKFDLLEKDIRKTHGAIENIGDLLNIPKPVRIEAFDNSNIQGTSPVAAMVV
FVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVMRDGLTPPDLIIIDGGQGQVNVARDVIENKLGLDIPIAGLQ
KNDKHQTHELLFGDPLEVIPLPRNSEEFFLLQRIQDEVHRFAITFHRQLRGKNTFSSKLNGIAGLGPKRKQLLMKHFKNL
PNIQKASLDDIINCGIPKNVAENIQESLREEREKG

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=506191 I6L88_RS03295 WP_002263201.1 657211..658998(+) (uvrC) [Streptococcus mutans strain FDAARGOS 1458]
ATGAACGAACTGATTAAACATAAGCTGGAATTGCTGCCAGATAGTCCTGGCTGTTATATTCACAAGGATAAAAACGGCAC
CATTATCTATGTCGGTAAGGCCAAGAACTTAAAAAACCGTGTGCGTAGCTATTTTCACGGCAGCCATAATACCAAGACAG
AATTGTTGGTTTCGGAAATTGAGGATTTTGAATACATTGTTACTGGGTCAAATACAGAAGCTTTACTTCTTGAGATTAAT
CTCATTCAGGAAAATAAGCCCAAGTACAATATCAGACTCAAAGATGATAAGTCTTATCCTTTTATTAAAATTACCAATGA
ACCTTATCCGCGTTTATTGATTACCCGTCAGGTGAAAAAGGATGGCGGTCTTTATTTTGGTCCCTACCCTGATTCGGGAG
CTGCTACTGAAATTAAGCGACTTTTAGATCGTCTCTTTCCCTTTAAAAAATGCACCAACCCAGCCAACAAGGTCTGTTTT
TATTATCATCTCGGGCAATGCAAGGCGCATACCATTTGTCAGACCGACCAAACCTATTGGGATAGTCTTAAAGAAGATGT
GAAAAACTTTCTCAATGGCAGGGACGATAAGATTGTCAATGAACTGCGCGATAAAATGACCAAAGCTTCTGAGCTCATGG
AATTTGAACGTGCAGCTGAATACCGAGATCTTATTGAGGGCATTGGTCTGTTGCGAACTAAGCAGCGCGTCATGAATCAG
GATATGCAGGATCGTGATATTTTTGGTTATTATGTTGATAAAGGCTGGATGTGTGTGCAGGTTTTCTTTATTCGTCAGGG
AAAGCTTATTCAGCGCGATGTCAATATGTTTCCTTATTACAATGAGTCTGAGGAAGATTTTCTGACCTATGTAGGACAGT
TCTATCAGGATAACCGTCACTTTATTCCAAAGGAGATTTTTATTCCTAGAAATATTGATGAAACTTTGGTTAAAGCGGTG
GTCAATACTAAGATTATCAAACCGCAGCGCGGCGAGAAGAAGCAGTTAGTCAATCTGGCAACGAAAAATGCTCGTGTTAG
CCTGCAGCAGAAATTTGATCTCTTGGAAAAAGATATTCGAAAAACGCATGGTGCGATTGAAAATATTGGAGATTTACTTA
ATATTCCTAAGCCAGTGCGCATTGAAGCCTTTGATAATTCCAACATTCAAGGAACCAGTCCTGTTGCAGCTATGGTTGTT
TTTGTGGACGGCAAGCCAAGTAAGAAGGATTATCGTAAATTTAAAATCAAAACCGTTATCGGACCTGATGACTATGCCAG
CATGCGTGAGGTTATTTATCGCAGATATAGCCGTGTCATGCGAGATGGACTGACACCACCAGACCTGATTATTATTGATG
GGGGACAAGGTCAGGTTAATGTAGCGCGTGACGTTATCGAAAATAAATTGGGACTCGATATTCCTATCGCTGGTTTGCAA
AAAAATGATAAGCACCAAACCCATGAGCTGCTCTTTGGTGATCCGCTGGAAGTGATTCCTCTGCCTAGAAATTCAGAAGA
GTTCTTTCTCTTGCAGCGCATTCAAGACGAAGTGCATCGCTTTGCCATTACATTTCATAGGCAGCTGCGCGGTAAAAACA
CCTTCTCATCAAAGTTGAACGGTATTGCAGGGCTCGGCCCTAAGCGCAAGCAATTGCTGATGAAACACTTTAAGAATCTT
CCTAATATTCAAAAGGCCAGCCTAGATGATATTATCAACTGCGGCATTCCAAAAAATGTCGCAGAGAACATTCAAGAGAG
CTTGCGAGAGGAAAGAGAAAAAGGTTAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrB/uvrC motif (UVR)

(196-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8CWX4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.728

99.664

0.765
  uvrC Streptococcus pneumoniae R6

76.391

99.664

0.761
  uvrC Streptococcus pneumoniae D39

76.391

99.664

0.761