Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   I6L84_RS08015 Genome accession   NZ_CP077224
Coordinates   1627421..1628053 (-) Length   210 a.a.
NCBI ID   WP_060552932.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS 1454     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1622421..1633053
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L84_RS07990 (I6L84_07990) comFA/cflA 1622494..1623795 (-) 1302 WP_060552928.1 DEAD/DEAH box helicase Machinery gene
  I6L84_RS07995 (I6L84_07995) - 1623851..1624483 (+) 633 WP_060552929.1 YigZ family protein -
  I6L84_RS08000 (I6L84_08000) cysK 1624581..1625510 (+) 930 WP_008808600.1 cysteine synthase A -
  I6L84_RS08005 (I6L84_08005) - 1625547..1625933 (-) 387 WP_060552930.1 S1 RNA-binding domain-containing protein -
  I6L84_RS08010 (I6L84_08010) - 1625930..1627333 (-) 1404 WP_060552931.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  I6L84_RS08015 (I6L84_08015) vraR 1627421..1628053 (-) 633 WP_060552932.1 response regulator transcription factor Regulator
  I6L84_RS08020 (I6L84_08020) - 1628055..1629056 (-) 1002 WP_060552933.1 sensor histidine kinase -
  I6L84_RS08025 (I6L84_08025) liaF 1629053..1629751 (-) 699 WP_060553303.1 cell wall-active antibiotics response protein LiaF -
  I6L84_RS08030 (I6L84_08030) stkP 1629927..1631774 (-) 1848 WP_060552934.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  I6L84_RS08035 (I6L84_08035) - 1631771..1632511 (-) 741 WP_060553304.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23777.36 Da        Isoelectric Point: 4.8067

>NTDB_id=505837 I6L84_RS08015 WP_060552932.1 1627421..1628053(-) (vraR) [Streptococcus gordonii strain FDAARGOS 1454]
MKILLVDDHEMVRLGLKSYLDLQADVEVVAESSNGREGVELALELRPDVIIMDIVMPEMNGIEATMAILETWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADEILHAIRKVARGEIAIETEVSKKVQYHRNHIELHDDLTARERDILGLLAKGY
ENQRIADELYISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQEDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=505837 I6L84_RS08015 WP_060552932.1 1627421..1628053(-) (vraR) [Streptococcus gordonii strain FDAARGOS 1454]
ATGAAAATTTTATTAGTAGATGATCACGAAATGGTTCGTTTGGGATTAAAAAGCTACCTAGACTTACAAGCAGATGTTGA
AGTGGTGGCAGAAAGTTCTAATGGCCGTGAGGGAGTTGAGCTGGCTTTGGAGCTAAGACCAGATGTCATCATCATGGATA
TTGTTATGCCAGAGATGAATGGTATCGAGGCTACTATGGCTATTCTAGAAACTTGGCCAGAGGCAAAGATTTTGATTTTG
ACTTCCTACTTGGATAATGAAAAGATTTATCCTGTTCTGGATGCTGGAGCTAAAGGTTACATGCTGAAGACATCTAGTGC
AGATGAGATCTTACATGCTATCCGAAAAGTAGCTAGAGGAGAAATTGCGATTGAAACAGAAGTCAGCAAAAAAGTTCAGT
ACCATCGCAATCACATTGAATTACATGATGATTTAACCGCCCGAGAACGAGATATTTTGGGGCTTCTAGCCAAGGGCTAT
GAAAATCAACGCATTGCTGATGAACTTTATATTTCTCTAAAAACAGTAAAAACTCATGTTTCTAATATCTTATCAAAATT
GGAAGTGAGCGACCGGACTCAAGCGGTTGTCTATGCCTTCCAGCATCACTTAGTTCCTCAGGAAGACTTTTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.095

0.529
  degU Bacillus subtilis subsp. subtilis str. 168

39.732

100

0.424