Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   I6L84_RS00650 Genome accession   NZ_CP077224
Coordinates   117004..118947 (+) Length   647 a.a.
NCBI ID   WP_060554247.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS 1454     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 112004..123947
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L84_RS00630 (I6L84_00630) - 113755..114528 (+) 774 WP_248842273.1 zinc ribbon domain-containing protein -
  I6L84_RS00635 (I6L84_00635) - 114572..115879 (+) 1308 WP_060554250.1 SPFH domain-containing protein -
  I6L84_RS00640 (I6L84_00640) - 115912..116382 (-) 471 WP_060554249.1 DUF3021 family protein -
  I6L84_RS00645 (I6L84_00645) brsR 116379..116819 (-) 441 WP_060554248.1 LytTR family DNA-binding domain-containing protein Regulator
  I6L84_RS00650 (I6L84_00650) hexB 117004..118947 (+) 1944 WP_060554247.1 DNA mismatch repair endonuclease MutL Machinery gene
  I6L84_RS00655 (I6L84_00655) - 118984..119505 (-) 522 WP_060554246.1 RDD family protein -
  I6L84_RS00660 (I6L84_00660) - 119489..119992 (-) 504 WP_060554245.1 helix-turn-helix domain-containing protein -
  I6L84_RS00665 (I6L84_00665) ruvA 120162..120755 (+) 594 WP_060554244.1 Holliday junction branch migration protein RuvA Machinery gene
  I6L84_RS00670 (I6L84_00670) - 120765..121319 (+) 555 WP_060554243.1 DNA-3-methyladenine glycosylase I -
  I6L84_RS00675 (I6L84_00675) - 121324..121983 (+) 660 WP_060554242.1 CPBP family intramembrane glutamic endopeptidase -
  I6L84_RS00680 (I6L84_00680) - 122034..122444 (-) 411 WP_060554241.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 73303.44 Da        Isoelectric Point: 5.0766

>NTDB_id=505754 I6L84_RS00650 WP_060554247.1 117004..118947(+) (hexB) [Streptococcus gordonii strain FDAARGOS 1454]
MSKIIELPEILANQIAAGEVIERPSSVVKELVENSLDAGASQITIEIEEAGLKTIQVTDNGEGIDHEDVPLALRRHATSK
IKKQADLFRIRTLGFRGEAIPSIASVSRFTIETATENGQHGTLLVAQGGEIEEHEPTSSPVGTKIKIEDLFFNTPARLKY
MKSQQAELSHIVDVINRLSLAHPEVAFTLISDGREMTRTAGSGNLRQAIAGIYGLATAKKMVEISASDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPLAVINIQIDPYLADVNVHPTKQEVRISKERELMALISQ
AIAASLKEQDLIPDALENLAKSTVKRATKPEQTSLPLKENRLYYDKERNDFFLKPEVAEQQLSFEESAKPIHEATDEKAE
PQPTSVKFAERKPASYDQLDHPELDQVSLERAVDKLEQEEKSSFPELEYFGQMHGTYLFAQGKGGLYIIDQHAAQERVKY
EYYREKIGDVDNSQQQLLVPYIFEFPADDMLRIKQRMELLEDAGIFLEEYGANQFILREHPIWFKEEEIEAGIYEMCDML
LLTKEVSIKKYRAELAIMMSCKRSIKANHSLDDYSARDLLFQLSQCDNPYNCPHGRPVLVNFTKSDIEKMFRRIQENHTS
LRELGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=505754 I6L84_RS00650 WP_060554247.1 117004..118947(+) (hexB) [Streptococcus gordonii strain FDAARGOS 1454]
ATGTCAAAAATTATCGAACTTCCAGAAATTCTAGCCAATCAGATTGCGGCCGGTGAGGTCATTGAGCGACCTAGCAGCGT
GGTCAAGGAGCTGGTGGAAAATTCACTTGATGCGGGTGCTAGCCAAATTACCATTGAAATCGAGGAGGCCGGACTCAAGA
CTATCCAGGTGACGGATAATGGCGAGGGCATAGATCACGAAGATGTCCCTCTGGCCCTTCGCCGCCATGCTACCAGTAAA
ATCAAGAAACAGGCGGATCTCTTTCGGATTCGGACACTGGGTTTTCGCGGCGAGGCCATTCCTTCCATTGCTTCTGTCTC
GCGTTTTACCATTGAGACTGCAACAGAAAATGGCCAGCACGGGACTTTGCTAGTTGCCCAAGGCGGTGAGATAGAAGAGC
ATGAGCCTACCAGCAGTCCGGTGGGAACGAAAATCAAGATTGAGGATCTCTTCTTTAATACTCCAGCCCGGCTCAAGTAT
ATGAAGAGCCAGCAGGCTGAGCTGTCCCATATCGTTGATGTGATTAATCGGCTTAGTCTGGCCCATCCAGAAGTGGCTTT
CACCCTTATTAGTGACGGTCGCGAAATGACACGGACTGCTGGCAGTGGTAATCTGCGTCAGGCTATTGCAGGCATCTATG
GTTTGGCAACAGCTAAGAAAATGGTGGAAATATCTGCTTCAGATTTGGACTTTGAGGTGAGCGGCTATGTCAGTCTGCCT
GAGTTGACTCGTGCGAACCGCAATTATATTACGATTCTCATCAACGGCCGTTACATTAAGAATTTCCTGCTCAATCGTGC
TATTTTGGACGGCTACGGCAGCAAGCTTATGGTAGGTCGCTTTCCGCTAGCGGTCATCAATATTCAGATTGATCCTTACC
TAGCCGATGTCAATGTCCATCCGACCAAGCAAGAGGTGCGGATTTCTAAAGAACGGGAACTCATGGCCTTGATTTCGCAA
GCCATTGCGGCTAGTCTCAAGGAGCAGGACCTTATCCCAGATGCTTTGGAAAATCTAGCCAAATCAACTGTTAAGCGTGC
GACTAAACCCGAACAGACCAGTCTTCCTCTGAAAGAAAATCGCCTCTACTACGATAAGGAGCGGAATGACTTCTTCCTCA
AACCAGAGGTGGCAGAGCAGCAGTTATCCTTTGAAGAGTCAGCAAAGCCTATTCATGAAGCGACAGACGAAAAAGCAGAA
CCGCAACCGACTTCGGTCAAATTTGCAGAGAGAAAGCCGGCCAGCTATGACCAGTTAGACCATCCAGAGCTAGACCAGGT
CAGTCTGGAGCGAGCTGTAGATAAGTTGGAACAAGAAGAGAAGTCAAGCTTCCCAGAGTTAGAATATTTCGGTCAGATGC
ATGGCACCTATCTCTTTGCTCAGGGCAAGGGTGGCCTTTACATTATTGACCAGCATGCTGCCCAAGAGCGGGTCAAGTAT
GAGTATTATCGGGAGAAGATTGGGGATGTGGATAATAGCCAACAGCAGCTCTTGGTGCCCTATATCTTTGAATTTCCAGC
AGACGATATGCTGCGAATCAAGCAGCGGATGGAGCTGTTAGAAGATGCAGGCATCTTTTTAGAAGAGTACGGAGCTAACC
AGTTTATCCTCCGTGAGCATCCGATTTGGTTCAAGGAAGAGGAGATTGAGGCCGGCATCTATGAGATGTGTGATATGCTT
CTCTTGACCAAGGAAGTCTCCATCAAGAAATATCGAGCAGAGCTAGCTATTATGATGAGTTGCAAACGCTCCATCAAGGC
CAATCACAGTCTGGATGACTACTCTGCGCGTGACTTGCTCTTTCAGCTGTCCCAGTGTGACAATCCTTATAACTGCCCAC
ACGGCCGGCCGGTCTTGGTTAACTTTACCAAGTCGGATATAGAAAAAATGTTCCGCCGCATTCAGGAAAATCATACTAGC
CTACGGGAGTTGGGGAAATACTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(449-591)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

77.658

100

0.779