Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SII_RS06680 Genome accession   NC_022237
Coordinates   1375252..1375884 (-) Length   210 a.a.
NCBI ID   WP_003073662.1    Uniprot ID   -
Organism   Streptococcus intermedius C270     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1370252..1380884
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SII_RS06650 (SII_1309) - 1370625..1371401 (+) 777 WP_020998984.1 aminoglycoside 3'-phosphotransferase -
  SII_RS06655 (SII_1310) recX 1371465..1372241 (+) 777 WP_041823261.1 recombination regulator RecX -
  SII_RS06660 (SII_1311) - 1372328..1372861 (+) 534 WP_003073655.1 DUF402 domain-containing protein -
  SII_RS06665 (SII_1312) - 1372981..1373298 (+) 318 WP_003073656.1 DUF960 domain-containing protein -
  SII_RS06670 (SII_1313) - 1373418..1373810 (-) 393 WP_003073658.1 S1 RNA-binding domain-containing protein -
  SII_RS06675 (SII_1314) - 1373812..1375212 (-) 1401 WP_003073660.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SII_RS06680 (SII_1315) vraR 1375252..1375884 (-) 633 WP_003073662.1 response regulator transcription factor Regulator
  SII_RS06685 (SII_1316) - 1375886..1376881 (-) 996 WP_003073664.1 sensor histidine kinase -
  SII_RS06690 (SII_1317) liaF 1376878..1377576 (-) 699 WP_020998987.1 cell wall-active antibiotics response protein LiaF -
  SII_RS06695 (SII_1318) stkP 1377839..1379713 (-) 1875 WP_003073669.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SII_RS06700 (SII_1319) - 1379710..1380450 (-) 741 WP_020998988.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23710.39 Da        Isoelectric Point: 4.8916

>NTDB_id=50528 SII_RS06680 WP_003073662.1 1375252..1375884(-) (vraR) [Streptococcus intermedius C270]
MQILLVDDHEMVRLGLKSYLDVQDNVDMVVEASNGCEGVEKALSLRPDVIMMDIVMPKMNGIEATLAILKEWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADDILRAVRKVAKGELAIETEVSQKVEYHRNHIELHEELTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQDDI

Nucleotide


Download         Length: 633 bp        

>NTDB_id=50528 SII_RS06680 WP_003073662.1 1375252..1375884(-) (vraR) [Streptococcus intermedius C270]
ATGCAGATTTTATTAGTAGATGATCATGAAATGGTGCGACTTGGTTTGAAGAGCTATTTAGATGTACAAGATAATGTTGA
TATGGTGGTAGAAGCTTCAAATGGTTGTGAAGGGGTGGAAAAGGCTCTGTCATTACGACCAGATGTGATAATGATGGATA
TTGTCATGCCTAAAATGAATGGGATTGAAGCTACACTTGCTATTTTAAAAGAATGGCCTGAAGCTAAAATTCTTATTTTG
ACTTCTTATTTAGATAATGAAAAAATTTACCCAGTTTTAGATGCAGGGGCTAAAGGATACATGCTTAAAACATCTAGTGC
TGACGATATCTTACGAGCAGTTCGAAAGGTAGCCAAGGGTGAACTTGCTATTGAAACAGAGGTCAGTCAGAAAGTGGAAT
ACCATCGAAATCATATTGAATTACATGAAGAGCTAACAGCGCGTGAGCGCGATATTTTAGGTCTATTAGCAAAAGGGTAT
GAAAATCAACGGATAGCAGATGAGTTGTTTATTTCGTTGAAGACTGTTAAAACACATGTATCTAATATCTTATCAAAATT
AGAAGTAAGTGATCGGACACAAGCTGTTGTTTACGCCTTTCAGCACCACCTTGTCCCACAAGATGACATTTAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.398

98.095

0.524
  degU Bacillus subtilis subsp. subtilis str. 168

38.839

100

0.414

Multiple sequence alignment