Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   HPSH417_RS00190 Genome accession   NC_017739
Coordinates   33707..34450 (+) Length   247 a.a.
NCBI ID   WP_000660502.1    Uniprot ID   A0A0E0WAE9
Organism   Helicobacter pylori Shi417     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 28707..39450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPSH417_RS00170 (HPSH417_00155) panD 30848..31198 (+) 351 WP_000142504.1 aspartate 1-decarboxylase -
  HPSH417_RS00175 (HPSH417_00160) - 31209..31511 (+) 303 WP_000347918.1 YbaB/EbfC family nucleoid-associated protein -
  HPSH417_RS00180 (HPSH417_00165) - 31511..32518 (+) 1008 WP_000468453.1 PDZ domain-containing protein -
  HPSH417_RS00185 (HPSH417_00170) comB6 32526..33581 (+) 1056 WP_000786671.1 P-type conjugative transfer protein TrbL Machinery gene
  HPSH417_RS08005 comB7 33597..33710 (+) 114 WP_001217864.1 hypothetical protein Machinery gene
  HPSH417_RS00190 (HPSH417_00175) comB8 33707..34450 (+) 744 WP_000660502.1 type IV secretion system protein Machinery gene
  HPSH417_RS00195 (HPSH417_00180) comB9 34450..35415 (+) 966 WP_014661897.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HPSH417_RS00200 (HPSH417_00185) comB10 35408..36544 (+) 1137 WP_001045876.1 DNA type IV secretion system protein ComB10 Machinery gene
  HPSH417_RS00205 (HPSH417_00190) - 36614..38026 (+) 1413 WP_000694822.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HPSH417_RS00210 (HPSH417_00195) gmd 38041..39186 (+) 1146 WP_000659885.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28599.81 Da        Isoelectric Point: 8.9830

>NTDB_id=50487 HPSH417_RS00190 WP_000660502.1 33707..34450(+) (comB8) [Helicobacter pylori Shi417]
MKEKPFNSEQLAFLEELLSHQEKHLENKLSGFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIALILAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIALSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=50487 HPSH417_RS00190 WP_000660502.1 33707..34450(+) (comB8) [Helicobacter pylori Shi417]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGGCTTTTTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAGTGATTTGGACATGCAAAGCGTGTTCAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGTTTGATGAGTTTTATCGCTCTTATCTTGGCGATCGTGTTAATCAGTGTTTTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCTAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACAGGGAGAGCATTAATCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCGCAAAGCCATCTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTACCAGCAAGACAATAACCCCATTGCGAGCGT
TTCTATTGCAGCTAAACTCATGAATGAAAACAAGCTAGTTTATGAAAAGCGTTATAAAATCGCGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCCAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E0WAE9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.166

100

0.972

Multiple sequence alignment