Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/comE3   Type   Machinery gene
Locus tag   HCW_RS00990 Genome accession   NC_017737
Coordinates   181890..183209 (-) Length   439 a.a.
NCBI ID   WP_014660365.1    Uniprot ID   I0EKM3
Organism   Helicobacter cetorum MIT 00-7128     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 176890..188209
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HCW_RS00960 (HCW_00965) nadA 177638..178648 (-) 1011 WP_014660359.1 quinolinate synthase NadA -
  HCW_RS00965 (HCW_00970) - 178638..179453 (-) 816 WP_043902546.1 phosphatidylserine decarboxylase -
  HCW_RS00970 (HCW_00975) - 179450..179953 (-) 504 WP_014660361.1 DUF6115 domain-containing protein -
  HCW_RS00975 (HCW_00980) - 179968..180456 (-) 489 WP_014660362.1 hypothetical protein -
  HCW_RS00980 (HCW_00985) mqnP 180449..181309 (-) 861 WP_231283044.1 menaquinone biosynthesis prenyltransferase MqnP -
  HCW_RS00985 (HCW_00990) - 181334..181879 (-) 546 WP_043902548.1 DUF502 domain-containing protein -
  HCW_RS00990 (HCW_00995) comEC/comE3 181890..183209 (-) 1320 WP_014660365.1 ComEC/Rec2 family competence protein Machinery gene
  HCW_RS00995 (HCW_01000) - 183206..184669 (-) 1464 WP_014660366.1 replicative DNA helicase -
  HCW_RS01000 (HCW_01005) - 184660..186078 (-) 1419 WP_014660367.1 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase -
  HCW_RS01010 (HCW_01015) - 187015..188157 (-) 1143 WP_043902549.1 restriction endonuclease subunit S -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50898.96 Da        Isoelectric Point: 10.0026

>NTDB_id=50467 HCW_RS00990 WP_014660365.1 181890..183209(-) (comEC/comE3) [Helicobacter cetorum MIT 00-7128]
MKTTSFKGAFDLLTTPKESLVCFVILGLLFAFNLYLEYSNYKKLDFSKPMSFNAQILLQYPKMKNQKSYFVLKLKSAQGH
IFYTTTKEPLKNLQYRYARFFGKVMPCNFLQSLKSCYFHTYSFSLLHKQDFKAHLRNFIDSMHSNDFISNLYRALFLGDS
LNKDLRDRANSLGINHLLAISGFHLGILSATLYFLLSLFYKPLQNRYFPYRNAFFDVGVLVWVFMLGYLVLLDFLPSFFR
AFLMGLLGFLACFFGIRLLSFKLLILASLIAIALLPKLLFSVGFLLSVCGVWYIFLFLKHAKAFFKDNSLLRRFIQAISL
SVLVFFNMLIVVHAFFPMFSFYQLLSIPLGFVFVVFFPLSLFLHAINLGHLLDNFLNTPLEIPTISIHTPLWLLGVFLCL
TLLSVRFFKAYLSMNILSVSFFLYCCYQYIIMPSLIVGN

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=50467 HCW_RS00990 WP_014660365.1 181890..183209(-) (comEC/comE3) [Helicobacter cetorum MIT 00-7128]
TTGAAAACCACATCTTTTAAGGGGGCGTTTGATTTACTCACAACCCCCAAAGAGAGCTTAGTATGTTTTGTCATTTTAGG
CTTATTGTTTGCTTTTAATCTCTATTTAGAATACTCTAATTACAAAAAACTTGATTTTTCAAAGCCCATGAGTTTCAACG
CTCAAATTTTATTGCAATACCCTAAGATGAAAAACCAAAAATCTTATTTTGTCTTAAAACTCAAATCCGCTCAAGGTCAT
ATTTTTTACACCACTACAAAAGAGCCTTTAAAAAATCTTCAATACCGCTACGCACGATTTTTTGGTAAGGTTATGCCTTG
TAATTTTTTGCAATCTTTGAAATCATGCTATTTTCACACCTATTCTTTTTCTTTATTGCACAAGCAAGATTTTAAAGCTC
ATTTACGCAATTTTATTGATAGCATGCATTCAAACGACTTTATCAGCAATTTGTATCGGGCGTTGTTTTTGGGCGATAGT
CTGAATAAAGATTTAAGAGATAGGGCTAATTCTTTAGGCATTAACCACCTACTAGCCATTAGTGGGTTTCATTTAGGCAT
TTTGAGTGCCACACTTTATTTTCTTTTGTCTCTCTTTTATAAGCCCTTGCAAAATCGCTATTTTCCCTATAGGAACGCCT
TTTTTGATGTGGGGGTTTTAGTCTGGGTTTTTATGCTAGGTTATTTAGTGCTATTAGATTTTTTGCCATCTTTTTTTAGG
GCGTTTTTAATGGGCTTACTAGGGTTTTTAGCATGCTTTTTTGGCATAAGGCTACTAAGTTTCAAGCTCTTGATTTTAGC
AAGCCTTATCGCCATTGCCCTACTACCTAAATTGCTTTTTAGTGTGGGGTTTTTGCTCTCAGTTTGTGGGGTGTGGTATA
TCTTTTTATTTTTAAAACATGCGAAAGCTTTTTTTAAAGATAACTCTCTTTTAAGGCGATTTATTCAAGCCATAAGCTTA
AGCGTTTTGGTGTTTTTTAACATGCTTATTGTTGTGCATGCCTTTTTTCCTATGTTTTCATTTTATCAACTCCTTAGCAT
TCCTTTAGGCTTTGTTTTTGTGGTGTTTTTTCCTTTGAGTTTATTCTTGCATGCAATCAATTTGGGGCATCTATTAGATA
ATTTTTTAAATACGCCTTTAGAAATTCCTACTATTTCAATTCATACACCTTTGTGGCTCTTAGGGGTGTTTTTGTGCTTA
ACACTTCTTAGTGTTCGTTTTTTTAAAGCCTATTTAAGCATGAATATTTTAAGCGTTAGCTTTTTCTTGTATTGTTGCTA
TCAATATATTATAATGCCTAGTTTAATTGTAGGGAATTAA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(158-424)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0EKM3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/comE3 Helicobacter pylori 26695

78.311

99.772

0.781

Multiple sequence alignment