Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | IXH55_RS07545 | Genome accession | NZ_CP064772 |
| Coordinates | 1559813..1561441 (+) | Length | 542 a.a. |
| NCBI ID | WP_001631035.1 | Uniprot ID | - |
| Organism | Staphylococcus aureus strain TCH32767 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1537796..1566048 | 1559813..1561441 | within | 0 |
| SCCmec | 1521940..1561441 | 1559813..1561441 | within | 0 |
Gene organization within MGE regions
Location: 1521940..1566048
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IXH55_RS07355 (IXH55_07290) | ccrA | 1521940..1523289 (+) | 1350 | WP_000815646.1 | recombinase family protein | Machinery gene |
| IXH55_RS07360 (IXH55_07295) | ccrB | 1523311..1524939 (+) | 1629 | WP_001186602.1 | recombinase family protein | Machinery gene |
| IXH55_RS07365 (IXH55_07300) | - | 1525457..1525807 (+) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| IXH55_RS07370 (IXH55_07305) | - | 1525894..1526205 (+) | 312 | WP_000700853.1 | DUF960 family protein | - |
| IXH55_RS07375 (IXH55_07310) | - | 1526223..1526729 (+) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| IXH55_RS07380 (IXH55_07315) | - | 1526750..1527067 (+) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| IXH55_RS07385 (IXH55_07320) | - | 1527186..1528271 (+) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| IXH55_RS07390 (IXH55_07325) | - | 1528268..1530160 (+) | 1893 | WP_001557544.1 | site-specific integrase | - |
| IXH55_RS07395 (IXH55_07330) | - | 1530167..1530544 (+) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| IXH55_RS07400 (IXH55_07335) | - | 1530695..1531477 (+) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| IXH55_RS07405 (IXH55_07340) | erm(A) | 1531603..1532334 (-) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| IXH55_RS07410 (IXH55_07350) | - | 1532830..1533492 (+) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| IXH55_RS07420 (IXH55_07360) | - | 1533837..1534475 (-) | 639 | Protein_1462 | sulfite exporter TauE/SafE family protein | - |
| IXH55_RS07425 (IXH55_07365) | cstR | 1534475..1534735 (-) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| IXH55_RS07430 (IXH55_07370) | - | 1534871..1535935 (+) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| IXH55_RS07435 (IXH55_07375) | cstB | 1535968..1537302 (+) | 1335 | Protein_1465 | persulfide dioxygenase-sulfurtransferase CstB | - |
| IXH55_RS07440 (IXH55_07380) | - | 1537416..1538525 (-) | 1110 | WP_000943131.1 | ROK family transcriptional regulator | - |
| IXH55_RS07445 (IXH55_07385) | psm-mec | 1538880..1538948 (+) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| IXH55_RS07450 (IXH55_07390) | mecI | 1539033..1539404 (-) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| IXH55_RS07455 (IXH55_07395) | mecR1 | 1539404..1541161 (-) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| IXH55_RS07460 (IXH55_07400) | mecA | 1541258..1543267 (+) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| IXH55_RS07465 (IXH55_07405) | - | 1543313..1543741 (-) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| IXH55_RS07470 (IXH55_07410) | - | 1543838..1544581 (-) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| IXH55_RS07475 (IXH55_07415) | - | 1544846..1545520 (+) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| IXH55_RS07480 (IXH55_07420) | aadD1 | 1545713..1546483 (+) | 771 | WP_001795128.1 | aminoglycoside O-nucleotidyltransferase ANT(4')-Ia | - |
| IXH55_RS07485 (IXH55_07425) | bleO | 1546700..1547104 (+) | 405 | WP_001242578.1 | bleomycin binding protein | - |
| IXH55_RS07490 (IXH55_07430) | mobV | 1547611..1548873 (+) | 1263 | WP_000119405.1 | MobV family relaxase | - |
| IXH55_RS07495 (IXH55_07435) | - | 1549118..1550101 (+) | 984 | Protein_1477 | protein rep | - |
| IXH55_RS07500 (IXH55_07445) | - | 1550192..1550866 (+) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| IXH55_RS07505 (IXH55_07450) | - | 1550898..1551137 (-) | 240 | WP_001282728.1 | hypothetical protein | - |
| IXH55_RS07510 (IXH55_07455) | - | 1551552..1552808 (-) | 1257 | WP_000566670.1 | DUF3578 domain-containing protein | - |
| IXH55_RS07515 (IXH55_07460) | - | 1554034..1555959 (-) | 1926 | WP_031783917.1 | heavy metal translocating P-type ATPase | - |
| IXH55_RS07520 (IXH55_07465) | - | 1556289..1556615 (-) | 327 | WP_000391495.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| IXH55_RS07525 (IXH55_07470) | - | 1556822..1557181 (+) | 360 | WP_001631039.1 | hypothetical protein | - |
| IXH55_RS07530 (IXH55_07475) | - | 1557293..1557631 (-) | 339 | Protein_1484 | recombinase family protein | - |
| IXH55_RS07535 (IXH55_07480) | - | 1557640..1558269 (+) | 630 | Protein_1485 | hypothetical protein | - |
| IXH55_RS07540 (IXH55_07485) | - | 1558456..1559816 (+) | 1361 | Protein_1486 | recombinase family protein | - |
| IXH55_RS07545 (IXH55_07490) | ccrB | 1559813..1561441 (+) | 1629 | WP_001631035.1 | recombinase family protein | Machinery gene |
| IXH55_RS07550 (IXH55_07495) | - | 1561942..1562292 (+) | 351 | WP_001631034.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| IXH55_RS07555 (IXH55_07500) | - | 1562379..1562690 (+) | 312 | WP_001631033.1 | DUF960 domain-containing protein | - |
| IXH55_RS07560 (IXH55_07505) | - | 1562706..1563209 (+) | 504 | WP_001631032.1 | DUF1643 domain-containing protein | - |
| IXH55_RS07565 (IXH55_07510) | - | 1563224..1563444 (+) | 221 | Protein_1491 | hypothetical protein | - |
| IXH55_RS07570 (IXH55_07515) | - | 1563607..1564017 (+) | 411 | WP_001631031.1 | DUF2871 domain-containing protein | - |
| IXH55_RS07575 (IXH55_07525) | - | 1564689..1565186 (+) | 498 | WP_001631030.1 | GNAT family N-acetyltransferase | - |
| IXH55_RS07580 (IXH55_07530) | - | 1565248..1565464 (+) | 217 | Protein_1494 | IS5/IS1182 family transposase | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62474.71 Da Isoelectric Point: 9.6103
>NTDB_id=504642 IXH55_RS07545 WP_001631035.1 1559813..1561441(+) (ccrB) [Staphylococcus aureus strain TCH32767]
MKQLKKKRIGLYARVSTEMQTDGYSIQGQLNQLTEYCQFQGYEVVNEYTDRGISGKTMQRPELQRMLKDANEGKLDCIMV
YKTNRLARNTSDLLNIVEELYKINVEFFSLTEKIEIASSTGKLMLQILASFAEFERNTIVENVYNGQRQRAIEGYYQGNL
PLGYDKVPDSKKELMINQHEANIVKYIFDSYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYIISNPFYIGKIQFAKY
RHWSDKRRKGLNEEPIIADGKHAPIIDRNLWDKVQFKRQESRKKPQVHGKGTNLLTGIVKCPKCGAAMAASNTTNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSVRADVLEKYVMDQILEIIKSKKVLKQLVEKVNEKSQIDVSSLNHDIAYKQSQCEE
IKAKMHTLTKTIEDSPDLDSVLKPTILSYQDELNQINNQIYQLEQDKQAEAPHYDADMIANVLQAIFKDIDKLEKSQLKS
LYLTIIDRIDIRKDEHHKKQFYVTLKLNNDIIKQLFNNHPLDEVLPSTSSLFLPQTLYITIE
MKQLKKKRIGLYARVSTEMQTDGYSIQGQLNQLTEYCQFQGYEVVNEYTDRGISGKTMQRPELQRMLKDANEGKLDCIMV
YKTNRLARNTSDLLNIVEELYKINVEFFSLTEKIEIASSTGKLMLQILASFAEFERNTIVENVYNGQRQRAIEGYYQGNL
PLGYDKVPDSKKELMINQHEANIVKYIFDSYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYIISNPFYIGKIQFAKY
RHWSDKRRKGLNEEPIIADGKHAPIIDRNLWDKVQFKRQESRKKPQVHGKGTNLLTGIVKCPKCGAAMAASNTTNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSVRADVLEKYVMDQILEIIKSKKVLKQLVEKVNEKSQIDVSSLNHDIAYKQSQCEE
IKAKMHTLTKTIEDSPDLDSVLKPTILSYQDELNQINNQIYQLEQDKQAEAPHYDADMIANVLQAIFKDIDKLEKSQLKS
LYLTIIDRIDIRKDEHHKKQFYVTLKLNNDIIKQLFNNHPLDEVLPSTSSLFLPQTLYITIE
Nucleotide
Download Length: 1629 bp
>NTDB_id=504642 IXH55_RS07545 WP_001631035.1 1559813..1561441(+) (ccrB) [Staphylococcus aureus strain TCH32767]
ATGAAACAACTCAAAAAGAAACGTATTGGATTATATGCACGTGTATCGACTGAAATGCAAACGGATGGTTACAGTATTCA
AGGTCAATTGAATCAACTTACAGAGTATTGTCAATTTCAAGGCTATGAAGTCGTCAATGAATACACCGATCGTGGTATAT
CAGGTAAAACAATGCAACGTCCAGAATTACAACGTATGTTAAAAGATGCCAACGAAGGTAAATTAGATTGTATTATGGTC
TACAAAACAAATCGTTTAGCTAGAAATACCTCAGATTTGTTAAATATTGTCGAGGAATTGTATAAGATTAATGTCGAATT
TTTTAGTCTAACTGAAAAAATAGAAATTGCCAGTTCAACAGGTAAATTGATGCTCCAAATTTTAGCCAGCTTCGCAGAAT
TTGAACGTAATACGATTGTAGAGAATGTCTACAATGGCCAAAGACAACGTGCTATTGAAGGTTATTATCAAGGTAATTTA
CCTCTAGGCTACGATAAAGTACCTGACAGTAAAAAAGAGCTCATGATCAATCAACATGAAGCGAATATTGTTAAATATAT
TTTTGATTCATACGCTAAAGGTCATGGTTATCGTAAGATTGCGAACGCATTGAATCATAAAGGTTATGTGACTAAGAAAG
GGAAACCTTTTAGTATTTCGTCCATTACCTACATCATCTCAAACCCTTTTTACATTGGAAAGATACAGTTTGCGAAGTAT
AGACACTGGAGCGATAAAAGACGAAAAGGACTCAATGAGGAACCGATTATCGCTGATGGTAAACATGCGCCTATTATTGA
TAGAAACCTATGGGATAAAGTACAGTTTAAACGTCAAGAGAGTCGCAAGAAACCACAAGTTCACGGCAAAGGAACAAACC
TACTGACTGGGATTGTAAAATGTCCGAAATGTGGTGCAGCAATGGCGGCAAGTAATACAACTAATACATTAAAAGATGGC
ACTAAGAAAAGAATCAGATATTACTCATGTAGCAATTTTAGAAATAAAGGTTCAAAAGTTTGTTCTGCCAATAGCGTTAG
AGCAGATGTACTAGAAAAATATGTTATGGATCAGATATTGGAAATTATCAAAAGCAAAAAGGTATTGAAGCAATTGGTTG
AAAAGGTAAATGAAAAAAGTCAAATAGACGTCTCTTCTTTGAACCATGATATTGCCTATAAACAGTCACAATGTGAAGAA
ATAAAAGCAAAAATGCATACATTAACGAAAACTATTGAAGACTCACCTGACTTAGATAGCGTATTAAAACCAACAATACT
TAGCTACCAAGATGAATTGAATCAAATAAATAATCAAATCTATCAACTAGAACAAGATAAACAAGCAGAAGCTCCACATT
ATGATGCTGATATGATTGCGAATGTACTACAAGCAATATTCAAAGATATAGACAAATTAGAGAAATCTCAGTTGAAATCA
CTATATCTAACAATCATCGATCGCATTGACATAAGAAAAGATGAGCATCATAAGAAGCAATTTTATGTTACGCTCAAGTT
AAATAATGATATAATCAAACAACTATTTAATAACCATCCACTCGACGAAGTGCTCCCTAGCACTTCGTCTTTATTTTTGC
CACAAACTTTATATATAACTATTGAATAA
ATGAAACAACTCAAAAAGAAACGTATTGGATTATATGCACGTGTATCGACTGAAATGCAAACGGATGGTTACAGTATTCA
AGGTCAATTGAATCAACTTACAGAGTATTGTCAATTTCAAGGCTATGAAGTCGTCAATGAATACACCGATCGTGGTATAT
CAGGTAAAACAATGCAACGTCCAGAATTACAACGTATGTTAAAAGATGCCAACGAAGGTAAATTAGATTGTATTATGGTC
TACAAAACAAATCGTTTAGCTAGAAATACCTCAGATTTGTTAAATATTGTCGAGGAATTGTATAAGATTAATGTCGAATT
TTTTAGTCTAACTGAAAAAATAGAAATTGCCAGTTCAACAGGTAAATTGATGCTCCAAATTTTAGCCAGCTTCGCAGAAT
TTGAACGTAATACGATTGTAGAGAATGTCTACAATGGCCAAAGACAACGTGCTATTGAAGGTTATTATCAAGGTAATTTA
CCTCTAGGCTACGATAAAGTACCTGACAGTAAAAAAGAGCTCATGATCAATCAACATGAAGCGAATATTGTTAAATATAT
TTTTGATTCATACGCTAAAGGTCATGGTTATCGTAAGATTGCGAACGCATTGAATCATAAAGGTTATGTGACTAAGAAAG
GGAAACCTTTTAGTATTTCGTCCATTACCTACATCATCTCAAACCCTTTTTACATTGGAAAGATACAGTTTGCGAAGTAT
AGACACTGGAGCGATAAAAGACGAAAAGGACTCAATGAGGAACCGATTATCGCTGATGGTAAACATGCGCCTATTATTGA
TAGAAACCTATGGGATAAAGTACAGTTTAAACGTCAAGAGAGTCGCAAGAAACCACAAGTTCACGGCAAAGGAACAAACC
TACTGACTGGGATTGTAAAATGTCCGAAATGTGGTGCAGCAATGGCGGCAAGTAATACAACTAATACATTAAAAGATGGC
ACTAAGAAAAGAATCAGATATTACTCATGTAGCAATTTTAGAAATAAAGGTTCAAAAGTTTGTTCTGCCAATAGCGTTAG
AGCAGATGTACTAGAAAAATATGTTATGGATCAGATATTGGAAATTATCAAAAGCAAAAAGGTATTGAAGCAATTGGTTG
AAAAGGTAAATGAAAAAAGTCAAATAGACGTCTCTTCTTTGAACCATGATATTGCCTATAAACAGTCACAATGTGAAGAA
ATAAAAGCAAAAATGCATACATTAACGAAAACTATTGAAGACTCACCTGACTTAGATAGCGTATTAAAACCAACAATACT
TAGCTACCAAGATGAATTGAATCAAATAAATAATCAAATCTATCAACTAGAACAAGATAAACAAGCAGAAGCTCCACATT
ATGATGCTGATATGATTGCGAATGTACTACAAGCAATATTCAAAGATATAGACAAATTAGAGAAATCTCAGTTGAAATCA
CTATATCTAACAATCATCGATCGCATTGACATAAGAAAAGATGAGCATCATAAGAAGCAATTTTATGTTACGCTCAAGTT
AAATAATGATATAATCAAACAACTATTTAATAACCATCCACTCGACGAAGTGCTCCCTAGCACTTCGTCTTTATTTTTGC
CACAAACTTTATATATAACTATTGAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
72.694 |
100 |
0.727 |