Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KQ220_RS10415 Genome accession   NZ_CP076709
Coordinates   2164392..2165048 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli O158:H23 strain CFIAFB20140388     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2159392..2170048
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KQ220_RS10385 (KQ220_10385) yecA 2160644..2161309 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  KQ220_RS10405 (KQ220_10405) pgsA 2161958..2162506 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KQ220_RS10410 (KQ220_10410) uvrC 2162563..2164395 (-) 1833 WP_001559273.1 excinuclease ABC subunit UvrC Machinery gene
  KQ220_RS10415 (KQ220_10415) letA 2164392..2165048 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KQ220_RS10420 (KQ220_10420) yecU 2165344..2165520 (+) 177 WP_000590347.1 protein YecU -
  KQ220_RS10425 (KQ220_10425) yecF 2165507..2165731 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  KQ220_RS10430 (KQ220_10430) sdiA 2165798..2166520 (-) 723 WP_001154281.1 transcriptional regulator SdiA -
  KQ220_RS10435 (KQ220_10435) tcyN 2166750..2167502 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KQ220_RS10440 (KQ220_10440) tcyL 2167499..2168167 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  KQ220_RS10445 (KQ220_10445) dcyD 2168182..2169168 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=504300 KQ220_RS10415 WP_000611328.1 2164392..2165048(-) (letA) [Escherichia coli O158:H23 strain CFIAFB20140388]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=504300 KQ220_RS10415 WP_000611328.1 2164392..2165048(-) (letA) [Escherichia coli O158:H23 strain CFIAFB20140388]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482