Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HPB14_RS00110 Genome accession   NC_017733
Coordinates   14140..16503 (+) Length   787 a.a.
NCBI ID   WP_000890498.1    Uniprot ID   -
Organism   Helicobacter pylori HUP-B14     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 9140..21503
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPB14_RS00080 (HPB14_00050) groES 9162..9518 (-) 357 WP_000671934.1 co-chaperone GroES -
  HPB14_RS00085 (HPB14_00055) dnaG 9804..11483 (+) 1680 WP_014658393.1 DNA primase -
  HPB14_RS00090 (HPB14_00060) - 11480..12532 (+) 1053 WP_000809466.1 MnmA/TRMU family protein -
  HPB14_RS00095 (HPB14_00065) - 12622..13449 (+) 828 WP_001154872.1 DUF5718 family protein -
  HPB14_RS00100 (HPB14_00070) comB2 13594..13875 (+) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  HPB14_RS00105 (HPB14_00075) comB3 13875..14138 (+) 264 WP_000584956.1 hypothetical protein Machinery gene
  HPB14_RS00110 (HPB14_00080) comB4 14140..16503 (+) 2364 WP_000890498.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HPB14_RS00115 (HPB14_00085) - 16801..18141 (+) 1341 WP_014658394.1 COG3014 family protein -
  HPB14_RS00120 (HPB14_00090) cheV1 18241..19206 (+) 966 WP_000785480.1 chemotaxis protein CheV1 -
  HPB14_RS00125 (HPB14_00095) nspC 19203..20420 (+) 1218 WP_000760852.1 carboxynorspermidine decarboxylase -
  HPB14_RS00130 (HPB14_00100) lpxE 20417..20950 (-) 534 WP_229018048.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90262.72 Da        Isoelectric Point: 7.9936

>NTDB_id=50423 HPB14_RS00110 WP_000890498.1 14140..16503(+) (comB4) [Helicobacter pylori HUP-B14]
MLEKLLSAIKQKVSNYFLGVLPKSYSMNEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDHQQNIQSDSQYLQAILNQFENKEVYENQYFLVLESTHSLQGVLEHKKKSLMHANKENFKDILS
YKAHFLQETLKSLEIQLKNYAPKILSSKEVLNFYAEYINGFDLPLKPLVWGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAIGALLYQETPLDIIFSIEPMSVHKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNVLIKAPSLEDLDAQTSLVLGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLVIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTEFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMLDLAPSRDKEALEDMNAVSGAIKSLYETLYPKAFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSNAFLNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHHFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLESLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=50423 HPB14_RS00110 WP_000890498.1 14140..16503(+) (comB4) [Helicobacter pylori HUP-B14]
ATGTTAGAAAAGCTTTTGAGCGCTATCAAGCAAAAAGTTTCAAACTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCTAT
GAACGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTTTTACTCACTAAAAACGAAAACTTAGTGGGTATTCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACTGAGCGCCAGATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGCACGCCTGGTGGTTAAAAGGCGTAAAATTGATCACCAACAAAACATTCAATCTGATTCTCA
ATACTTGCAAGCGATTTTGAATCAATTTGAAAACAAAGAAGTGTATGAGAATCAGTATTTTTTAGTTTTAGAAAGCACGC
ACTCCTTACAAGGTGTTTTGGAGCATAAGAAAAAATCTCTCATGCATGCCAATAAGGAAAATTTTAAGGATATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCCTAGAAATCCAGCTCAAAAACTATGCCCCCAAAATCTTAAGCTC
TAAAGAGGTTTTGAATTTTTATGCGGAATATATCAATGGGTTTGATCTCCCTTTAAAACCCCTAGTATGGGGGTATTTGA
GCGATAGCTATATCGCTAGTTCTATCACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAACCAAAAAACCTATAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAACGCATCACTTCTATAGCGATCGGAGCGCTTTTATACCAAGAGACGCC
ACTAGATATTATCTTTTCTATAGAGCCTATGAGTGTGCATAAAACGCTGAGTTTTTTAAAAGAGAGAGCCAAGTTTAGCA
TGTCTAATCTCGTTAAAAACGAGCTGCTAGAATACCAAGAATTGGTCAAAACCAAACGCCTATCCATGCAAAAATTCGCC
CTAAACGTTCTTATCAAAGCCCCTAGTTTAGAGGATTTAGACGCTCAAACGAGCTTAGTTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCATTTAAACC
ACCGCTTGCGTTTTTTGACCTCTAAAGCCCTAGCGTGTTTGATGGTGTTTGAAAGGCAAAATTTAGGCTTTAAAGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCATAATAACGCTAAAGAAATTGCCAGAGTGAATGGGCATACTTTAGTTATAGGGGCAACCGGAAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTAAAATACCAAAACATGCGCCTTTTAGCTTTTGACAGGATGCAAGGGCTG
TATTCTTTCACCGAATTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATTAATCCCTTTTGTTTAGAGCCTAA
TTTACAGAATTTAGAATTTTTGCAATCCTTTTTTTTGAGCATGTTGGATCTCGCCCCTTCAAGGGATAAAGAAGCCTTAG
AAGACATGAATGCGGTTTCTGGTGCGATTAAGAGCCTTTATGAGACCTTATACCCTAAAGCCTTTAGTTTGCTAGACTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAATTGGGCTTGAGTTTAGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCATTCAATTCCAACGCTTTTTTAAATGTAATCAACTTAGACGCTATCACCCAAAACCCTAAAGACTTAG
GACTTTTAGCCTATTACTTGTTTTATAAAATTTTAGAAGAATCCAGGAAAAACGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTATTGAACACCAAAATCAACGCTTTAATCACGCAAGCCAGGAAAGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGATATTTACCAGTTAAGCGGGGTCAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTCATTTTGTATCCGCAAAAAAACGCTAGGGAGTTGAAACACCACTTCAATGTGCCTTTGAGCGAGACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAACGGGAGTTCTAACATGATTGATGT
GAGTTTGGAGAGCTTGGGGCGTTATTTGAAAATCTTTAATTCGGATTCTAGTCATGTGAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGTTAG

Domains

Predicted by InterproScan.

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.84

100

0.978

Multiple sequence alignment