Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KQ217_RS03250 Genome accession   NZ_CP076706
Coordinates   636585..637241 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli O170:H18 strain CFIAFB20120266     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 631585..642241
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KQ217_RS03220 (KQ217_03220) yecA 632837..633502 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  KQ217_RS03240 (KQ217_03240) pgsA 634151..634699 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KQ217_RS03245 (KQ217_03245) uvrC 634756..636588 (-) 1833 WP_161997271.1 excinuclease ABC subunit UvrC Machinery gene
  KQ217_RS03250 (KQ217_03250) letA 636585..637241 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KQ217_RS03255 (KQ217_03255) yecU 637537..637713 (+) 177 WP_001307856.1 protein YecU -
  KQ217_RS03260 (KQ217_03260) yecF 637700..637924 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  KQ217_RS03265 (KQ217_03265) sdiA 637992..638714 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  KQ217_RS03270 (KQ217_03270) tcyN 638944..639696 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KQ217_RS03275 (KQ217_03275) tcyL 639693..640361 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  KQ217_RS03280 (KQ217_03280) dcyD 640376..641362 (-) 987 WP_097420662.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=504196 KQ217_RS03250 WP_000611328.1 636585..637241(-) (letA) [Escherichia coli O170:H18 strain CFIAFB20120266]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=504196 KQ217_RS03250 WP_000611328.1 636585..637241(-) (letA) [Escherichia coli O170:H18 strain CFIAFB20120266]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482