Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KQ221_RS09215 Genome accession   NZ_CP076704
Coordinates   1918545..1919201 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O8:H28 strain BMH-17-0027     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1913545..1924201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KQ221_RS09185 (KQ221_09185) dcyD 1914425..1915411 (+) 987 WP_001128219.1 D-cysteine desulfhydrase -
  KQ221_RS09190 (KQ221_09190) tcyL 1915426..1916094 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KQ221_RS09195 (KQ221_09195) tcyN 1916091..1916843 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KQ221_RS09200 (KQ221_09200) sdiA 1917073..1917795 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  KQ221_RS09205 (KQ221_09205) yecF 1917862..1918086 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KQ221_RS09210 (KQ221_09210) yecU 1918073..1918249 (-) 177 WP_000590347.1 protein YecU -
  KQ221_RS24095 - 1918332..1918403 (-) 72 Protein_1803 transcriptional regulator -
  KQ221_RS09215 (KQ221_09215) letA 1918545..1919201 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KQ221_RS09220 (KQ221_09220) uvrC 1919198..1921030 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  KQ221_RS09225 (KQ221_09225) pgsA 1921087..1921635 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KQ221_RS09245 (KQ221_09245) yecA 1922285..1922950 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=504148 KQ221_RS09215 WP_000611335.1 1918545..1919201(+) (letA) [Escherichia coli O8:H28 strain BMH-17-0027]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=504148 KQ221_RS09215 WP_000611335.1 1918545..1919201(+) (letA) [Escherichia coli O8:H28 strain BMH-17-0027]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486