Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   KRG72_RS02375 Genome accession   NZ_CP076703
Coordinates   449678..450322 (+) Length   214 a.a.
NCBI ID   WP_006531177.1    Uniprot ID   A0ABP2DKG8
Organism   Streptococcus equinus strain S1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 444678..455322
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KRG72_RS02355 (KRG72_02355) - 445253..445990 (+) 738 WP_074482688.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  KRG72_RS02360 (KRG72_02360) stkP/pknB 445990..447879 (+) 1890 WP_258255706.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  KRG72_RS02365 (KRG72_02365) liaF 447977..448672 (+) 696 WP_039695888.1 cell wall-active antibiotics response protein LiaF -
  KRG72_RS02370 (KRG72_02370) - 448669..449694 (+) 1026 WP_258255711.1 sensor histidine kinase -
  KRG72_RS02375 (KRG72_02375) vraR 449678..450322 (+) 645 WP_006531177.1 response regulator transcription factor Regulator
  KRG72_RS02380 (KRG72_02380) - 450446..451846 (+) 1401 WP_081341909.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  KRG72_RS02385 (KRG72_02385) - 451846..452202 (+) 357 WP_020916316.1 S1 RNA-binding domain-containing protein -
  KRG72_RS02390 (KRG72_02390) cysK 452302..453231 (-) 930 WP_074561282.1 cysteine synthase A -
  KRG72_RS02395 (KRG72_02395) - 453331..453957 (-) 627 WP_258255720.1 YigZ family protein -
  KRG72_RS02400 (KRG72_02400) comFA/cflA 454012..455310 (+) 1299 WP_258255721.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24025.88 Da        Isoelectric Point: 5.0501

>NTDB_id=504035 KRG72_RS02375 WP_006531177.1 449678..450322(+) (vraR) [Streptococcus equinus strain S1]
MTQKIRVILVDDHEMVRLGLKSFFNLQPDVEVVGEAGNGIEGIKLALELKPDVVVMDLVMPEMSGVEATLKLLKEWKEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVARGELAIETEVDKKIKAHDQKPELHEDLTARERDILRLL
AKGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFKHHLVPQDED

Nucleotide


Download         Length: 645 bp        

>NTDB_id=504035 KRG72_RS02375 WP_006531177.1 449678..450322(+) (vraR) [Streptococcus equinus strain S1]
ATGACCCAGAAAATTAGAGTTATCCTAGTTGATGACCACGAAATGGTACGTCTTGGTTTGAAAAGTTTTTTTAACTTGCA
ACCTGACGTTGAAGTTGTTGGCGAAGCAGGCAATGGCATTGAAGGGATAAAACTTGCTTTAGAGTTAAAACCAGATGTGG
TAGTAATGGATTTGGTAATGCCTGAAATGAGTGGCGTTGAAGCGACCTTAAAACTCTTAAAAGAGTGGAAAGAAGCTAAA
ATCCTTGTTCTGACATCTTATCTTGATAATGAAAAAATCTACCCAGTTATTGAAGCAGGTGCTAAAGGTTATATGTTAAA
AACATCTAGTGCCGCTGAAATTCTTAATGCTATCCAAAAAGTGGCGCGTGGTGAATTAGCAATCGAGACAGAGGTTGATA
AGAAAATCAAAGCCCACGATCAGAAACCAGAATTGCATGAAGATTTGACAGCGCGTGAACGAGATATTTTAAGACTTCTT
GCTAAAGGTTATGACAATCAGACCATTGCTGATGAATTGTTTATTTCACTAAAAACAGTTAAAACCCACGTGTCAAACAT
CTTAGCTAAGCTAGAAGTAGATGACCGCACACAAGCAGTTGTCTATGCCTTTAAGCATCATTTAGTACCGCAAGATGAGG
ATTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-119)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.427

96.262

0.505
  degU Bacillus subtilis subsp. subtilis str. 168

37.946

100

0.397