Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   HWI22_RS04740 Genome accession   NZ_CP064606
Coordinates   942993..943865 (+) Length   290 a.a.
NCBI ID   WP_002484839.1    Uniprot ID   A0A4Y7VXK4
Organism   Staphylococcus epidermidis strain UMCG349     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 937993..948865
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HWI22_RS04715 (HWI22_04660) - 938176..938325 (+) 150 WP_162154119.1 hypothetical protein -
  HWI22_RS04720 (HWI22_04665) ylqF 938346..939209 (+) 864 WP_001829495.1 ribosome biogenesis GTPase YlqF -
  HWI22_RS04725 (HWI22_04670) - 939214..939984 (+) 771 WP_001829514.1 ribonuclease HII -
  HWI22_RS04730 (HWI22_04675) sucC 940092..941258 (+) 1167 WP_002439496.1 ADP-forming succinate--CoA ligase subunit beta -
  HWI22_RS04735 (HWI22_04680) sucD 941280..942188 (+) 909 WP_002446283.1 succinate--CoA ligase subunit alpha -
  HWI22_RS04740 (HWI22_04685) dprA 942993..943865 (+) 873 WP_002484839.1 DNA-processing protein DprA Machinery gene
  HWI22_RS04745 (HWI22_04690) topA 944048..946117 (+) 2070 WP_001829508.1 type I DNA topoisomerase -
  HWI22_RS04750 (HWI22_04695) trmFO 946142..947449 (+) 1308 WP_001832560.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  HWI22_RS04755 (HWI22_04700) xerC 947704..948564 (+) 861 WP_002439503.1 tyrosine recombinase XerC -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33717.61 Da        Isoelectric Point: 9.3616

>NTDB_id=503487 HWI22_RS04740 WP_002484839.1 942993..943865(+) (dprA) [Staphylococcus epidermidis strain UMCG349]
MIQQTMLKLYWANFTTAQLHHLTSTYPDFLSENVFHQHDMIKRWLTERNSERLWNKYERFKELKLMDIIKEMKKANVSFT
TYFDDNYPSLCKEMYDYPYVIFYKGNPQFFNHSHSLAVIGSRNATQYTSQSLNYLFPSFRQLNMAIVSGLARGADSVAHQ
TALKYLLPTIGVLGFGHCYHYPKATLNLRTKVERNGLVISEYPPFSPISKHKFPERNRLISGLSRGVLITEAEERSGSQI
TIDCALEQNRNVYVLPGSMFNKMTKGNLRRINEGAQVVIDESSILYDYLF

Nucleotide


Download         Length: 873 bp        

>NTDB_id=503487 HWI22_RS04740 WP_002484839.1 942993..943865(+) (dprA) [Staphylococcus epidermidis strain UMCG349]
TTGATACAACAGACGATGTTAAAACTATATTGGGCAAATTTCACTACGGCACAACTTCATCATCTTACAAGTACATATCC
TGACTTTCTATCAGAAAACGTATTTCATCAACATGACATGATAAAAAGGTGGCTTACAGAGCGTAATTCTGAAAGGCTAT
GGAACAAATATGAACGTTTCAAAGAATTAAAGCTGATGGACATTATTAAAGAAATGAAAAAAGCAAATGTTAGTTTTACA
ACATACTTTGATGATAACTACCCTTCTCTTTGCAAAGAAATGTATGATTATCCTTATGTGATATTCTACAAAGGAAATCC
ACAGTTCTTTAATCATTCTCACTCTTTAGCTGTAATTGGCTCACGTAATGCCACACAATATACAAGTCAATCTTTAAACT
ATCTTTTTCCTTCATTTAGACAATTAAATATGGCGATTGTTTCTGGATTAGCGCGCGGTGCAGATAGTGTAGCACATCAA
ACCGCACTTAAATACCTATTACCAACTATTGGCGTACTTGGATTTGGCCATTGTTATCATTATCCTAAAGCAACCTTAAA
TTTAAGAACTAAAGTTGAAAGGAATGGCTTAGTGATAAGTGAATATCCACCATTTTCTCCTATAAGTAAGCATAAATTTC
CTGAAAGAAACAGGCTTATAAGTGGTCTGTCCAGAGGGGTACTTATAACTGAGGCTGAAGAAAGAAGTGGTAGTCAAATC
ACTATCGATTGTGCTTTAGAGCAAAATAGAAATGTTTATGTTCTACCTGGTTCAATGTTCAACAAAATGACTAAAGGTAA
TTTAAGAAGGATAAATGAAGGTGCTCAAGTTGTTATAGATGAAAGTAGTATATTATATGATTATCTATTTTAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4Y7VXK4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

56.944

99.31

0.566
  dprA Staphylococcus aureus N315

56.944

99.31

0.566