Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   HWI25_RS08665 Genome accession   NZ_CP064593
Coordinates   1856615..1857190 (-) Length   191 a.a.
NCBI ID   WP_001829272.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain UMCG352     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1851615..1862190
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HWI25_RS08620 (HWI25_08590) - 1852311..1852526 (+) 216 WP_001831694.1 TM2 domain-containing protein -
  HWI25_RS08625 - 1852630..1852746 (+) 117 WP_353955880.1 SAR1012 family small protein -
  HWI25_RS08630 (HWI25_08595) - 1853177..1853335 (+) 159 WP_001829449.1 hypothetical protein -
  HWI25_RS08635 (HWI25_08600) - 1853405..1853917 (-) 513 WP_224788133.1 LysE/ArgO family amino acid transporter -
  HWI25_RS08640 (HWI25_08605) - 1854025..1854366 (-) 342 WP_002456621.1 fatty acid desaturase -
  HWI25_RS08645 (HWI25_08610) - 1854579..1854815 (-) 237 WP_001829451.1 hypothetical protein -
  HWI25_RS08650 mobV 1855017..1855577 (-) 561 Protein_1670 MobV family relaxase -
  HWI25_RS08665 (HWI25_08635) comK/comK1 1856615..1857190 (-) 576 WP_001829272.1 competence protein ComK Regulator
  HWI25_RS08670 (HWI25_08640) - 1857405..1857623 (+) 219 WP_001829292.1 IDEAL domain-containing protein -
  HWI25_RS08675 (HWI25_08645) - 1857701..1858687 (-) 987 WP_001829269.1 lipoate--protein ligase -
  HWI25_RS08680 (HWI25_08650) - 1858892..1859077 (+) 186 WP_001829339.1 DUF2187 family protein -
  HWI25_RS08685 (HWI25_08655) - 1859083..1859685 (+) 603 WP_001829312.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  HWI25_RS08690 (HWI25_08660) - 1859788..1861293 (-) 1506 WP_001829277.1 bifunctional UDP-sugar hydrolase/5'-nucleotidase -

Sequence

Protein


Download         Length: 191 a.a.        Molecular weight: 22782.87 Da        Isoelectric Point: 9.2887

>NTDB_id=503391 HWI25_RS08665 WP_001829272.1 1856615..1857190(-) (comK/comK1) [Staphylococcus epidermidis strain UMCG352]
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN

Nucleotide


Download         Length: 576 bp        

>NTDB_id=503391 HWI25_RS08665 WP_001829272.1 1856615..1857190(-) (comK/comK1) [Staphylococcus epidermidis strain UMCG352]
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
AACAAATGGTACTGAAATTATCAGATTTGATCAAACTCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAATTTTATGGTAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATCTCTAGTAAACCACCT
ATTTTACTTACGCCTCTTTTTCCTACTTACTTTTTTCCAACTCACTCAGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCGTTAACGCTCA
ATGTATCATTTCATAGCTTGTGGCATCAATATACGAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCTTCTCTAAATATTTTCGAGGCGCTCTCACGCTACTCCCT
TTTTGAAGAAAATTAG

Domains

Predicted by InterproScan.

ComK protein (ComK)

(7-158)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

76.757

96.859

0.743
  comK/comK1 Staphylococcus aureus N315

76.757

96.859

0.743