Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   KPA27_RS00345 Genome accession   NZ_CP076517
Coordinates   60734..62671 (+) Length   645 a.a.
NCBI ID   WP_141587959.1    Uniprot ID   -
Organism   Streptococcus suis strain 39565     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 55734..67671
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KPA27_RS00330 (KPA27_00330) - 56606..57544 (-) 939 WP_024402114.1 IS4 family transposase -
  KPA27_RS00335 (KPA27_00335) - 57681..58901 (+) 1221 WP_172005365.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  KPA27_RS00340 (KPA27_00340) - 59092..60615 (+) 1524 WP_141587958.1 quinol oxidase -
  KPA27_RS00345 (KPA27_00345) hexB 60734..62671 (+) 1938 WP_141587959.1 DNA mismatch repair endonuclease MutL Machinery gene
  KPA27_RS00350 (KPA27_00350) ruvA 62710..63300 (+) 591 WP_074391042.1 Holliday junction branch migration protein RuvA Machinery gene
  KPA27_RS00355 (KPA27_00355) - 63554..64123 (+) 570 WP_024402110.1 DNA-3-methyladenine glycosylase I -
  KPA27_RS00360 (KPA27_00360) cinA 64160..65341 (+) 1182 WP_044681379.1 competence/damage-inducible protein A Machinery gene
  KPA27_RS00365 (KPA27_00365) recA 65393..66544 (+) 1152 WP_044679554.1 recombinase RecA Machinery gene
  KPA27_RS00370 (KPA27_00370) spx 66780..67178 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  KPA27_RS00375 (KPA27_00375) - 67278..67544 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72926.06 Da        Isoelectric Point: 5.1134

>NTDB_id=503116 KPA27_RS00345 WP_141587959.1 60734..62671(+) (hexB) [Streptococcus suis strain 39565]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKNQSDLFRIRTLGFRGEALPSIASVSQMVIETATADSAHGLHLEAKGGVIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEIAFALVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLREPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPVENK
HTSVQFAERQSVDSEDQEHPNLSAKELAKLADKLDREETSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALDLVHKMDALRQVGVNLEEYGANQFILREHPIWMKEEEIESGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=503116 KPA27_RS00345 WP_141587959.1 60734..62671(+) (hexB) [Streptococcus suis strain 39565]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCGGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTTAAAA
TGATTCAAATTACGGATAACGGTGAGGGGATTGCCCCTGATGAAGTAGCGCTTGCTCTCCGCCGTCACGCCACCAGTAAG
ATAAAAAATCAATCGGATTTGTTTCGTATTCGCACCCTCGGTTTTCGTGGAGAAGCTCTGCCTTCCATTGCTTCTGTCAG
TCAGATGGTTATTGAGACAGCTACGGCAGACTCTGCACATGGACTTCATTTGGAGGCCAAAGGTGGTGTCATCGAGAAAG
AGGAGCCCGTTAGTCGTCCAGTTGGTACGCAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAC
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGTCTAGCTCATCCGGAAATAGCTTT
TGCCTTAGTAAACGAAGGACGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCTTCTGCCAAAAAAATGGTTGAAATTGAGGCAGAAGACCTGGATTTTCAGATTTCAGGTTATGTTTCCTTGCCA
GAGTTGACTCGTGCCAACCGCAACTACATTTCCATTTTCATCAATGGTCGCTATATCAAGAATTTTTTGCTGAATCGAGC
GATTTTGGAAGGTTATGGTAGTAAGTTGATGGTTGGACGCTTTCCGCTGGCAGTGATTTCTATAGAAATTGACCCCTATC
TTGCTGATGTCAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCGCTTAAAGAGCAGGACTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAGAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTCTTCTTAA
AACCAGACGTGGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGTCGAAAATAAA
CATACATCTGTTCAATTTGCAGAACGTCAGTCGGTGGATTCAGAAGATCAGGAGCATCCTAATCTAAGCGCAAAAGAATT
GGCAAAACTGGCAGATAAATTAGACCGGGAGGAAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAGATGCACGGGA
CGTATTTATTTGCACAAGGCAAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAGAGGGTCAAATACGAATAC
TACCGTGAGAAAATTGGACAGGTTGACAATTCAGCTCAACAGTTATTGGTGCCCTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTGACCTCGTCCACAAAATGGATGCCCTTCGTCAAGTTGGTGTCAACTTGGAAGAATATGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAGGAGATTGAGTCTGGCATCTATGAGATGTGTGACATGTTGCTCTTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCTATCATGATGTCTTGTAAACGGTCAATCAAGGCCAACCA
TGCTTTGGATGATTATTCGGCGCGTGATTTATTGAGACAATTGTCTTACTGCCAAAATCCCTATAATTGCCCGCACGGTC
GTCCAGTTTTAGTGCATTTTAGCAAGTCGGACATGGAAAAAATGTTCCGTCGCATTCAAGAAAATCACACAAGTTTGCGA
GAATTGGGCAAGTATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(447-589)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.462

100

0.73