Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KN807_RS17985 Genome accession   NZ_CP076470
Coordinates   3749065..3749721 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain DH5a     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3744065..3754721
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KN807_RS17955 (KN807_17905) dcyD 3744944..3745930 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  KN807_RS17960 (KN807_17910) tcyL 3745945..3746613 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KN807_RS17965 (KN807_17915) tcyN 3746610..3747362 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KN807_RS17970 (KN807_17920) sdiA 3747592..3748314 (+) 723 WP_001152715.1 transcriptional regulator SdiA -
  KN807_RS17975 (KN807_17925) yecF 3748382..3748606 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KN807_RS17980 (KN807_17930) yecU 3748593..3748769 (-) 177 WP_000590347.1 protein YecU -
  KN807_RS22470 - 3748852..3748923 (-) 72 Protein_3508 transcriptional regulator -
  KN807_RS17985 (KN807_17935) letA 3749065..3749721 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KN807_RS17990 (KN807_17940) uvrC 3749718..3751550 (+) 1833 WP_001283395.1 excinuclease ABC subunit UvrC Machinery gene
  KN807_RS17995 (KN807_17945) pgsA 3751607..3752155 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KN807_RS18015 (KN807_17965) yecA 3752805..3753470 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=502775 KN807_RS17985 WP_000611335.1 3749065..3749721(+) (letA) [Escherichia coli strain DH5a]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=502775 KN807_RS17985 WP_000611335.1 3749065..3749721(+) (letA) [Escherichia coli strain DH5a]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486