Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   HWI44_RS03420 Genome accession   NZ_CP064525
Coordinates   696277..696852 (+) Length   191 a.a.
NCBI ID   WP_001829272.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain UMCG371     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 691277..701852
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HWI44_RS03395 (HWI44_03355) - 692174..693679 (+) 1506 WP_001829277.1 bifunctional UDP-sugar hydrolase/5'-nucleotidase -
  HWI44_RS03400 (HWI44_03360) - 693782..694384 (-) 603 WP_001829312.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  HWI44_RS03405 (HWI44_03365) - 694390..694575 (-) 186 WP_001829339.1 DUF2187 family protein -
  HWI44_RS03410 (HWI44_03370) - 694780..695766 (+) 987 WP_001829269.1 lipoate--protein ligase -
  HWI44_RS03415 (HWI44_03375) - 695844..696062 (-) 219 WP_001829292.1 IDEAL domain-containing protein -
  HWI44_RS03420 (HWI44_03380) comK/comK1 696277..696852 (+) 576 WP_001829272.1 competence protein ComK Regulator
  HWI44_RS03435 (HWI44_03395) - 697253..698302 (-) 1050 WP_002504795.1 site-specific integrase -
  HWI44_RS03440 (HWI44_03400) - 698413..698610 (+) 198 WP_002497576.1 hypothetical protein -
  HWI44_RS03445 (HWI44_03405) - 698607..699014 (-) 408 WP_002497577.1 TIR domain-containing protein -
  HWI44_RS03450 (HWI44_03410) - 699008..699445 (-) 438 WP_002497578.1 DUF4231 domain-containing protein -
  HWI44_RS03455 (HWI44_03415) - 699557..700225 (-) 669 WP_002504794.1 hypothetical protein -
  HWI44_RS03460 (HWI44_03420) - 700243..700701 (-) 459 WP_002504200.1 ImmA/IrrE family metallo-endopeptidase -
  HWI44_RS03465 (HWI44_03425) - 700723..701037 (-) 315 WP_002504199.1 helix-turn-helix transcriptional regulator -
  HWI44_RS03470 (HWI44_03430) - 701190..701402 (+) 213 WP_002456362.1 helix-turn-helix transcriptional regulator -
  HWI44_RS03475 (HWI44_03435) - 701446..701586 (+) 141 WP_002485815.1 hypothetical protein -
  HWI44_RS03480 (HWI44_03440) - 701579..701803 (-) 225 WP_002504198.1 hypothetical protein -

Sequence

Protein


Download         Length: 191 a.a.        Molecular weight: 22782.87 Da        Isoelectric Point: 9.2887

>NTDB_id=502705 HWI44_RS03420 WP_001829272.1 696277..696852(+) (comK/comK1) [Staphylococcus epidermidis strain UMCG371]
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN

Nucleotide


Download         Length: 576 bp        

>NTDB_id=502705 HWI44_RS03420 WP_001829272.1 696277..696852(+) (comK/comK1) [Staphylococcus epidermidis strain UMCG371]
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
AACAAATGGTACTGAAATTATCAGATTTGATCAAACTCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAATTTTATGGTAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATCTCTAGTAAACCACCT
ATTTTACTTACGCCTCTTTTTCCTACTTACTTTTTTCCAACTCACTCAGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCGTTAACGCTCA
ATGTATCATTTCATAGCTTGTGGCATCAATATACGAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCTTCTCTAAATATTTTCGAGGCGCTCTCACGCTACTCCCT
TTTTGAAGAAAATTAG

Domains

Predicted by InterProScan.

ComK protein (ComK)

(7-158)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

76.757

96.859

0.743
  comK/comK1 Staphylococcus aureus N315

76.757

96.859

0.743