Detailed information NTG0502674

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: KME66_RS19085
• Genome accession: NZ_CP076457
• Coordinates: 4293691..4294815 (-)
• Length: 374 a.a.
• NCBI ID: WP_073225728.1
• Uniprot ID: -
• Organism: Streptomyces sp. YPW6
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4288691..4299815

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KME66_RS19060 (KME66_19060)	cseB	4288833..4289549 (-)	717	WP_216324020.1	two-component system response regulator CseB	-
KME66_RS19065 (KME66_19065)	-	4289717..4290364 (-)	648	WP_216329461.1	hypothetical protein	-
KME66_RS19070 (KME66_19070)	-	4290469..4291131 (-)	663	WP_216324023.1	SigE family RNA polymerase sigma factor	-
KME66_RS19075 (KME66_19075)	-	4291393..4292307 (-)	915	WP_216324027.1	A/G-specific adenine glycosylase	-
KME66_RS19080 (KME66_19080)	-	4292612..4293346 (+)	735	WP_216324030.1	hypothetical protein	-
KME66_RS19085 (KME66_19085)	disA	4293691..4294815 (-)	1125	WP_073225728.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
KME66_RS19090 (KME66_19090)	radA/sms	4294896..4296317 (-)	1422	WP_073226325.1	DNA repair protein RadA	Machinery gene
KME66_RS19095 (KME66_19095)	-	4296551..4298485 (+)	1935	WP_216324033.1	hypothetical protein	-
KME66_RS19100 (KME66_19100)	-	4298838..4299701 (-)	864	WP_073225724.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40396.35 Da
• Isoelectric Point: 4.9406

>NTDB_id=502674 KME66_RS19085 WP_073225728.1 4293691..4294815(-) (disA) [Streptomyces sp. YPW6]
MAANDRATTPGKSGQGTGNEALMRASLSAVAPGMALRDGLERILRGNTGGLIVLGMDRTVESMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDMTKILRAGVQLVPDASIPTEETGTRHRTADRVSKACGFPVVSVSQSMRLIALYVDGERRVLEESSA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVAEALTELDSLTHTELLELPVVARALGYSGSPETLDSAVSPRGFRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQAVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=502674 KME66_RS19085 WP_073225728.1 4293691..4294815(-) (disA) [Streptomyces sp. YPW6]
GTGGCAGCCAACGACCGGGCGACGACGCCCGGAAAGTCCGGCCAAGGCACCGGTAACGAGGCGCTGATGCGCGCCTCGCT
GAGCGCGGTCGCGCCCGGTATGGCCCTGCGGGACGGCCTGGAGCGCATTCTGCGCGGCAATACCGGCGGCCTGATCGTGC
TGGGCATGGACCGGACCGTCGAGTCGATGTGCACCGGCGGGTTCGTGCTGGACGTGGAGTTCACGGCGACGCGCCTGCGC
GAGCTGTGCAAGCTCGACGGAGCGCTGATCCTCGACAAGGACATGACCAAGATCCTGCGGGCCGGTGTGCAGCTGGTCCC
GGACGCGTCGATCCCCACGGAGGAGACGGGCACCCGGCACCGTACGGCGGACCGGGTCTCCAAGGCGTGCGGCTTCCCCG
TCGTCTCGGTCTCCCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGGGAGCGCCGGGTCCTGGAGGAGTCCTCCGCG
ATCCTGTCCCGGGCCAACCAGGCGCTCGCCACGCTGGAGCGGTACAAGCTGCGTCTCGACGAGGTCGCGGGCACGCTGTC
CGCGCTGGAGATCGAGGACCTGGTCACCGTCCGGGACGTGACGGCGGTGGCGCAGCGGCTGGAGATGGTGCGGCGGATCG
CGACGGAGATCGCGGAGTACGTGGTCGAGCTCGGCACCGACGGACGGCTGCTCTCCCTCCAGCTCGACGAGCTGATCGCG
GGGGTGGAGCCGGAGCGGGAGCTGGTCGTCCGGGACTACGTCCCCGAGCCGACGGCGAAACGGTCGCGCACGGTGGCCGA
GGCACTGACCGAGCTGGACTCCCTGACCCACACGGAGCTGCTGGAGCTGCCGGTGGTGGCGCGGGCGCTGGGCTACAGCG
GCTCGCCGGAGACGCTGGACTCGGCGGTGTCGCCGCGGGGCTTCCGGCTGCTGGCGAAGGTGCCGCGGCTGCCGGGGGCG
ATCATCGAGCGGCTGGTGGAGCACTTCGGGGGGCTGCAGAAGCTGCTGGCCGCCAGCGTGGACGATCTCCAGGCGGTGGA
CGGGGTCGGCGAGGCGCGGGCGCGGAGTGTTCGCGAGGGGCTGTCACGGCTGGCGGAGTCGTCGATCCTGGAGCGGTACG
TCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	44.875	96.524	0.433