Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   HWI46_RS07700 Genome accession   NZ_CP064519
Coordinates   1637166..1638038 (-) Length   290 a.a.
NCBI ID   WP_001829468.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain UMCG373     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1632467..1669552 1637166..1638038 within 0


Gene organization within MGE regions


Location: 1632467..1669552
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HWI46_RS07685 (HWI46_07625) xerC 1632467..1633327 (-) 861 WP_002439503.1 tyrosine recombinase XerC -
  HWI46_RS07690 (HWI46_07630) trmFO 1633582..1634889 (-) 1308 WP_001832560.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  HWI46_RS07695 (HWI46_07635) topA 1634914..1636983 (-) 2070 WP_001829508.1 type I DNA topoisomerase -
  HWI46_RS07700 (HWI46_07640) dprA 1637166..1638038 (-) 873 WP_001829468.1 DNA-processing protein DprA Machinery gene
  HWI46_RS07705 (HWI46_07645) sucD 1638844..1639752 (-) 909 WP_002446283.1 succinate--CoA ligase subunit alpha -
  HWI46_RS07710 (HWI46_07650) sucC 1639774..1640940 (-) 1167 WP_002456569.1 ADP-forming succinate--CoA ligase subunit beta -
  HWI46_RS07715 (HWI46_07655) - 1641048..1641818 (-) 771 WP_001829514.1 ribonuclease HII -
  HWI46_RS07720 (HWI46_07660) ylqF 1641823..1642686 (-) 864 WP_101021303.1 ribosome biogenesis GTPase YlqF -
  HWI46_RS07725 (HWI46_07665) - 1643015..1645615 (+) 2601 WP_002456571.1 YfhO family protein -
  HWI46_RS07730 (HWI46_07670) - 1645608..1648211 (+) 2604 WP_002456572.1 YfhO family protein -
  HWI46_RS07735 (HWI46_07675) rplS 1648741..1649091 (-) 351 WP_002436293.1 50S ribosomal protein L19 -
  HWI46_RS07740 (HWI46_07680) trmD 1649197..1649934 (-) 738 WP_001829466.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  HWI46_RS07745 (HWI46_07685) rimM 1649934..1650437 (-) 504 WP_001832559.1 ribosome maturation factor RimM -
  HWI46_RS07750 (HWI46_07690) rpsP 1650564..1650839 (-) 276 WP_002439483.1 30S ribosomal protein S16 -
  HWI46_RS07755 (HWI46_07695) ffh 1651147..1652514 (-) 1368 WP_001830113.1 signal recognition particle protein -
  HWI46_RS07760 (HWI46_07700) - 1652545..1652877 (-) 333 WP_002457379.1 putative DNA-binding protein -
  HWI46_RS07765 (HWI46_07705) ftsY 1652879..1654105 (-) 1227 WP_002456573.1 signal recognition particle-docking protein FtsY -
  HWI46_RS07770 (HWI46_07710) smc 1654102..1657671 (-) 3570 WP_002456574.1 chromosome segregation protein SMC -
  HWI46_RS07775 (HWI46_07715) rnc 1657798..1658535 (-) 738 WP_002456575.1 ribonuclease III -
  HWI46_RS07780 (HWI46_07720) - 1658650..1658883 (-) 234 WP_001830184.1 acyl carrier protein -
  HWI46_RS07785 (HWI46_07725) fabG 1659111..1659845 (-) 735 WP_001830161.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  HWI46_RS07790 (HWI46_07730) fabD 1659838..1660764 (-) 927 WP_002469385.1 ACP S-malonyltransferase -
  HWI46_RS07795 (HWI46_07735) plsX 1660766..1661743 (-) 978 WP_002469384.1 phosphate acyltransferase PlsX -
  HWI46_RS07800 (HWI46_07740) fapR 1661745..1662305 (-) 561 WP_001830099.1 transcription factor FapR -
  HWI46_RS07805 (HWI46_07745) recG 1662464..1664512 (-) 2049 WP_002456579.1 ATP-dependent DNA helicase RecG -
  HWI46_RS07810 (HWI46_07750) fakA 1664716..1666374 (-) 1659 WP_002456580.1 fatty acid kinase catalytic subunit FakA -
  HWI46_RS07815 (HWI46_07755) - 1666389..1666763 (-) 375 WP_001830156.1 Asp23/Gls24 family envelope stress response protein -
  HWI46_RS07820 (HWI46_07760) rpmB 1667121..1667309 (+) 189 WP_001830107.1 50S ribosomal protein L28 -
  HWI46_RS07825 (HWI46_07765) - 1667392..1668027 (-) 636 WP_001830164.1 thiamine diphosphokinase -
  HWI46_RS07830 (HWI46_07770) rpe 1668032..1668676 (-) 645 WP_002469381.1 ribulose-phosphate 3-epimerase -
  HWI46_RS07835 (HWI46_07775) rsgA 1668677..1669552 (-) 876 WP_002469378.1 ribosome small subunit-dependent GTPase A -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33726.62 Da        Isoelectric Point: 9.3618

>NTDB_id=502648 HWI46_RS07700 WP_001829468.1 1637166..1638038(-) (dprA) [Staphylococcus epidermidis strain UMCG373]
MIQHTMLKLYWANFTTAQLHHLTSTYPDFLSENVFHQHDMIKRWLTERNSERLWNKYERFKELKLMDIIKEMKKANVSFT
TYFDDNYPSLCKEMYDYPYVIFYKGNPQFFNHSHSLAVIGSRNATQYTSQSLNYLFPSFRQLNMAIVSGLARGADSVAHQ
TALKYLLPTIGVLGFGHCYHYPKATLNLRTKVERNGLVISEYPPFSPISKHKFPERNRLISGLSRGVLITEAEERSGSQI
TIDCALEQNRNVYVLPGSMFNKMTKGNLRRINEGAQVVIDESSILYDYLF

Nucleotide


Download         Length: 873 bp        

>NTDB_id=502648 HWI46_RS07700 WP_001829468.1 1637166..1638038(-) (dprA) [Staphylococcus epidermidis strain UMCG373]
TTGATACAACATACGATGTTAAAACTATATTGGGCAAATTTCACTACGGCACAACTTCATCATCTTACAAGTACATATCC
TGACTTTCTATCAGAAAACGTATTTCATCAACATGACATGATAAAAAGGTGGCTTACAGAGCGTAATTCTGAAAGGCTAT
GGAACAAATATGAACGTTTCAAAGAATTAAAGCTGATGGACATTATTAAAGAAATGAAAAAAGCAAATGTTAGTTTTACA
ACATACTTTGATGATAACTACCCTTCTCTTTGCAAAGAAATGTATGATTATCCTTATGTGATATTCTACAAAGGAAATCC
ACAGTTCTTTAATCATTCTCACTCTTTAGCTGTAATTGGCTCACGTAATGCCACACAATATACAAGTCAATCTTTAAACT
ATCTTTTTCCTTCATTTAGACAATTAAATATGGCGATTGTTTCTGGATTAGCGCGCGGTGCAGATAGTGTAGCACATCAA
ACCGCACTTAAATACCTATTACCAACTATTGGCGTACTTGGATTTGGCCATTGTTATCATTATCCTAAAGCAACCTTAAA
TTTAAGAACTAAAGTTGAAAGGAATGGCTTAGTGATAAGTGAATATCCACCATTTTCTCCTATAAGTAAGCATAAATTTC
CTGAAAGAAACAGGCTTATAAGTGGTCTGTCCAGAGGGGTACTTATAACTGAGGCTGAAGAAAGAAGTGGTAGTCAAATC
ACTATCGATTGTGCTTTAGAGCAAAATAGAAATGTTTATGTTCTACCTGGTTCAATGTTCAACAAAATGACTAAAGGTAA
TTTAAGAAGGATAAATGAAGGTGCTCAAGTTGTTATAGATGAAAGTAGTATATTATATGATTATCTATTTTAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus N315

56.944

99.31

0.566
  dprA Staphylococcus aureus MW2

56.944

99.31

0.566