Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   KNZ81_RS25390 Genome accession   NZ_CP076385
Coordinates   5748076..5748744 (+) Length   222 a.a.
NCBI ID   WP_215222456.1    Uniprot ID   -
Organism   Streptomyces sp. G11C(2021)     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5743076..5753744
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KNZ81_RS25375 (KNZ81_25180) - 5744750..5745472 (-) 723 WP_215222455.1 transglycosylase SLT domain-containing protein -
  KNZ81_RS31420 - 5745939..5746874 (-) 936 Protein_4981 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  KNZ81_RS25385 (KNZ81_25190) - 5746908..5748083 (+) 1176 WP_023420070.1 GAF domain-containing sensor histidine kinase -
  KNZ81_RS25390 (KNZ81_25195) vraR 5748076..5748744 (+) 669 WP_215222456.1 response regulator transcription factor Regulator
  KNZ81_RS25395 (KNZ81_25200) - 5748924..5749169 (+) 246 WP_023420072.1 chaplin -
  KNZ81_RS25400 (KNZ81_25205) - 5749247..5750020 (-) 774 WP_033953164.1 hypothetical protein -
  KNZ81_RS25405 (KNZ81_25210) - 5750151..5750948 (+) 798 WP_023420074.1 ABC transporter ATP-binding protein -
  KNZ81_RS25410 (KNZ81_25215) - 5751015..5751443 (+) 429 WP_003947359.1 NfeD family protein -
  KNZ81_RS25415 (KNZ81_25220) - 5751560..5752507 (+) 948 WP_008410203.1 SPFH domain-containing protein -
  KNZ81_RS25420 (KNZ81_25225) - 5752581..5753087 (-) 507 WP_003947357.1 HNH endonuclease -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24316.70 Da        Isoelectric Point: 5.9095

>NTDB_id=502339 KNZ81_RS25390 WP_215222456.1 5748076..5748744(+) (vraR) [Streptomyces sp. G11C(2021)]
MADTEREERHTQVIRVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAGDGAEGVARAEELQPDVVLMDVKMPGMDGVEALRR
LRELANPARVMVVTSFTEQRTVVPALRAGAGGYVYKDVDPEALARAIRSVHAGHVLLQPEVAGALLSQDEHGQGQGRGGS
LTEREREVLGLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGMAR

Nucleotide


Download         Length: 669 bp        

>NTDB_id=502339 KNZ81_RS25390 WP_215222456.1 5748076..5748744(+) (vraR) [Streptomyces sp. G11C(2021)]
GTGGCTGACACCGAGCGCGAGGAACGGCACACCCAGGTCATCCGGGTCCTCCTCGTCGACGACCACCAGGTGGTCCGCCG
CGGCCTGCGCACCTTCCTGGAGGTCCAGGACGACATCGAGGTGGTCGGCGAGGCCGGCGACGGCGCCGAAGGCGTGGCCC
GCGCCGAGGAGCTCCAGCCCGACGTCGTCCTGATGGACGTCAAGATGCCCGGCATGGACGGCGTCGAGGCCCTGCGCCGC
CTGCGGGAACTGGCCAACCCCGCCCGCGTCATGGTCGTCACCAGCTTCACCGAGCAGCGCACCGTGGTCCCCGCCCTGCG
CGCCGGCGCCGGGGGATACGTCTACAAGGACGTCGACCCCGAGGCACTGGCCCGCGCCATCCGCTCCGTCCACGCCGGTC
ACGTCCTCCTCCAGCCCGAGGTCGCCGGCGCCCTCCTCAGCCAGGACGAGCACGGCCAGGGCCAGGGGCGCGGCGGCTCC
CTGACCGAACGCGAACGCGAGGTGCTCGGCCTGATCGCCGACGGCCGCTCCAACCGCGAGATCGCCCGTGCCCTCGTCCT
CTCCGAGAAGACGGTGAAGACCCACGTCTCGAACATCCTGATGAAACTCGACCTCGCCGACCGCACCCAGGCCGCCCTGT
GGGCCGTACGCCACGGAATGGCACGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(160-215)

Response regulator receiver domain (Response_reg)

(16-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.928

93.243

0.419
  degU Bacillus subtilis subsp. subtilis str. 168

38.009

99.55

0.378