Detailed information NTG0502339

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: HWI54_RS04595
• Genome accession: NZ_CP064489
• Coordinates: 991348..992394 (+)
• Length: 348 a.a.
• NCBI ID: WP_002486322.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain UMCG381
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 986348..997394

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HWI54_RS04570 (HWI54_04565)	isaB	987489..988025 (+)	537	WP_001830372.1	immunodominant staphylococcal antigen IsaB family protein	-
HWI54_RS04575 (HWI54_04570)	-	988176..989162 (-)	987	WP_002457091.1	aromatic acid exporter family protein	-
HWI54_RS04580 (HWI54_04575)	map	989336..990091 (+)	756	WP_002457092.1	type I methionyl aminopeptidase	-
HWI54_RS04585 (HWI54_04580)	-	990249..990635 (+)	387	WP_001830382.1	hypothetical protein	-
HWI54_RS04590 (HWI54_04585)	liaF	990650..991351 (+)	702	WP_002457093.1	cell wall-active antibiotics response protein LiaF	-
HWI54_RS04595 (HWI54_04590)	vraS	991348..992394 (+)	1047	WP_002486322.1	sensor histidine kinase	Regulator
HWI54_RS04600 (HWI54_04595)	vraR	992384..993013 (+)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
HWI54_RS04605 (HWI54_04600)	-	993070..994248 (-)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
HWI54_RS04610 (HWI54_04605)	-	994655..994939 (-)	285	WP_001830401.1	YtxH domain-containing protein	-
HWI54_RS04615 (HWI54_04610)	-	994947..995411 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
HWI54_RS04620 (HWI54_04615)	-	995552..995767 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
HWI54_RS04625 (HWI54_04620)	-	995769..997010 (+)	1242	WP_002457094.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40039.46 Da
• Isoelectric Point: 5.8512

>NTDB_id=502339 HWI54_RS04595 WP_002486322.1 991348..992394(+) (vraS) [Staphylococcus epidermidis strain UMCG381]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVSIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=502339 HWI54_RS04595 WP_002486322.1 991348..992394(+) (vraS) [Staphylococcus epidermidis strain UMCG381]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAGTATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.733	98.851	0.917