Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   A7A12_RS09645 Genome accession   NZ_CP076285
Coordinates   1983809..1984465 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 41     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1978809..1989465
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7A12_RS09615 (A7A12_09620) yecA 1980060..1980725 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  A7A12_RS09635 (A7A12_09640) pgsA 1981375..1981923 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  A7A12_RS09640 (A7A12_09645) uvrC 1981980..1983812 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  A7A12_RS09645 (A7A12_09650) letA 1983809..1984465 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  A7A12_RS22590 - 1984607..1984678 (+) 72 Protein_1901 transcriptional regulator -
  A7A12_RS09650 (A7A12_09655) yecU 1984761..1984937 (+) 177 WP_000590347.1 protein YecU -
  A7A12_RS09655 (A7A12_09660) yecF 1984924..1985148 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  A7A12_RS09660 (A7A12_09665) sdiA 1985215..1985937 (-) 723 WP_001154279.1 transcriptional regulator SdiA -
  A7A12_RS09665 (A7A12_09670) tcyN 1986167..1986919 (-) 753 WP_001272992.1 L-cystine ABC transporter ATP-binding protein TcyN -
  A7A12_RS09670 (A7A12_09675) tcyL 1986916..1987584 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  A7A12_RS09675 (A7A12_09680) dcyD 1987599..1988585 (-) 987 WP_001128242.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=501892 A7A12_RS09645 WP_000611335.1 1983809..1984465(-) (letA) [Escherichia coli strain 41]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=501892 A7A12_RS09645 WP_000611335.1 1983809..1984465(-) (letA) [Escherichia coli strain 41]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486