Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   ECO55CA74_RS19965 Genome accession   NC_017656
Coordinates   3964647..3965771 (-) Length   374 a.a.
NCBI ID   WP_000228547.1    Uniprot ID   -
Organism   Escherichia coli O55:H7 str. RM12579     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 3959647..3970771
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ECO55CA74_RS19935 (ECO55CA74_19065) yrdA 3961447..3962001 (+) 555 WP_001286216.1 gamma carbonic anhydrase family protein -
  ECO55CA74_RS19940 (ECO55CA74_19070) yrdB 3961977..3962234 (-) 258 WP_001070590.1 DUF1488 domain-containing protein -
  ECO55CA74_RS19945 (ECO55CA74_19075) aroE 3962231..3963049 (-) 819 WP_000451254.1 shikimate dehydrogenase -
  ECO55CA74_RS19950 (ECO55CA74_19080) tsaC 3963054..3963626 (-) 573 WP_001301437.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  ECO55CA74_RS19955 (ECO55CA74_19085) yrdD 3963631..3964173 (-) 543 WP_001129722.1 type I DNA topoisomerase -
  ECO55CA74_RS19960 (ECO55CA74_19090) smg 3964202..3964675 (-) 474 WP_000460676.1 DUF494 family protein Smg -
  ECO55CA74_RS19965 (ECO55CA74_19095) dprA 3964647..3965771 (-) 1125 WP_000228547.1 DNA-protecting protein DprA Machinery gene
  ECO55CA74_RS19970 (ECO55CA74_19100) def 3965901..3966410 (+) 510 WP_000114985.1 peptide deformylase -
  ECO55CA74_RS19975 (ECO55CA74_19105) fmt 3966425..3967372 (+) 948 WP_000004459.1 methionyl-tRNA formyltransferase -
  ECO55CA74_RS19980 (ECO55CA74_19110) rsmB 3967418..3968707 (+) 1290 WP_001359006.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ECO55CA74_RS19985 (ECO55CA74_19115) trkA 3968729..3970105 (+) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  ECO55CA74_RS19990 (ECO55CA74_19120) mscL 3970235..3970645 (+) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40967.87 Da        Isoelectric Point: 6.2655

>NTDB_id=50186 ECO55CA74_RS19965 WP_000228547.1 3964647..3965771(-) (dprA) [Escherichia coli O55:H7 str. RM12579]
MVDTEIWLRLMSISSLYGDDMVRIAHWLARQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQSNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGATITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=50186 ECO55CA74_RS19965 WP_000228547.1 3964647..3965771(-) (dprA) [Escherichia coli O55:H7 str. RM12579]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAGACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGGAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAATCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGTGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCATGGAGCGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

49.051

98.663

0.484
  dprA Glaesserella parasuis strain SC1401

45.401

90.107

0.409
  dprA Vibrio cholerae strain A1552

49.355

82.888

0.409
  dprA Haemophilus influenzae Rd KW20

44.214

90.107

0.398
  dprA Legionella pneumophila strain ERS1305867

44.545

88.235

0.393

Multiple sequence alignment