Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   A7A19_RS10995 Genome accession   NZ_CP076279
Coordinates   2201321..2201977 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain SA53-3     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2196321..2206977
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7A19_RS10965 (A7A19_10915) yecA 2197573..2198238 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  A7A19_RS10985 (A7A19_10935) pgsA 2198887..2199435 (-) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  A7A19_RS10990 (A7A19_10940) uvrC 2199492..2201324 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  A7A19_RS10995 (A7A19_10945) letA 2201321..2201977 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  A7A19_RS26195 - 2202119..2202190 (+) 72 Protein_2166 transcriptional regulator -
  A7A19_RS11000 (A7A19_10950) yecU 2202273..2202449 (+) 177 WP_000590347.1 protein YecU -
  A7A19_RS11005 (A7A19_10955) yecF 2202436..2202660 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  A7A19_RS11010 (A7A19_10960) sdiA 2202727..2203449 (-) 723 WP_001154267.1 transcriptional regulator SdiA -
  A7A19_RS11015 (A7A19_10965) tcyN 2203679..2204431 (-) 753 WP_001272986.1 L-cystine ABC transporter ATP-binding protein TcyN -
  A7A19_RS11020 (A7A19_10970) tcyL 2204428..2205096 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  A7A19_RS11025 (A7A19_10975) dcyD 2205111..2206097 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=501735 A7A19_RS10995 WP_000611335.1 2201321..2201977(-) (letA) [Escherichia coli strain SA53-3]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=501735 A7A19_RS10995 WP_000611335.1 2201321..2201977(-) (letA) [Escherichia coli strain SA53-3]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486