Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   A7A21_RS18290 Genome accession   NZ_CP076276
Coordinates   3705767..3706399 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain SA31-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3700767..3711399
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7A21_RS18265 (A7A21_18210) yheS 3700936..3702849 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  A7A21_RS18270 (A7A21_18215) yheT 3702849..3703871 (+) 1023 WP_000057405.1 hydrolase -
  A7A21_RS18275 (A7A21_18220) yheU 3703865..3704083 (+) 219 WP_000907085.1 YheU family protein -
  A7A21_RS18280 (A7A21_18225) prkB 3704137..3705006 (+) 870 WP_001274680.1 phosphoribulokinase -
  A7A21_RS18285 (A7A21_18230) yhfA 3705061..3705465 (-) 405 WP_001148908.1 OsmC family protein -
  A7A21_RS18290 (A7A21_18235) crp 3705767..3706399 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  A7A21_RS18295 (A7A21_18240) yhfK 3706450..3708540 (+) 2091 WP_001345983.1 YccS/YhfK family putative transporter -
  A7A21_RS18300 (A7A21_18245) argD 3708607..3709827 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  A7A21_RS18305 (A7A21_18250) pabA 3709913..3710476 (-) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  A7A21_RS18310 (A7A21_18255) fic 3710508..3711110 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  A7A21_RS18315 (A7A21_18260) yhfG 3711100..3711267 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=501684 A7A21_RS18290 WP_000242755.1 3705767..3706399(+) (crp) [Escherichia coli strain SA31-1]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=501684 A7A21_RS18290 WP_000242755.1 3705767..3706399(+) (crp) [Escherichia coli strain SA31-1]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467