Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   A7A21_RS10705 Genome accession   NZ_CP076276
Coordinates   2164484..2165140 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain SA31-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2159484..2170140
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7A21_RS10675 (A7A21_10625) yecA 2160736..2161401 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  A7A21_RS10695 (A7A21_10645) pgsA 2162050..2162598 (-) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  A7A21_RS10700 (A7A21_10650) uvrC 2162655..2164487 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  A7A21_RS10705 (A7A21_10655) letA 2164484..2165140 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  A7A21_RS25220 - 2165282..2165353 (+) 72 Protein_2112 transcriptional regulator -
  A7A21_RS10710 (A7A21_10660) yecU 2165436..2165612 (+) 177 WP_000590347.1 protein YecU -
  A7A21_RS10715 (A7A21_10665) yecF 2165599..2165823 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  A7A21_RS10720 (A7A21_10670) sdiA 2165890..2166612 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  A7A21_RS10725 (A7A21_10675) tcyN 2166842..2167594 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  A7A21_RS10730 (A7A21_10680) tcyL 2167591..2168259 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  A7A21_RS10735 (A7A21_10685) dcyD 2168274..2169260 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=501656 A7A21_RS10705 WP_000611335.1 2164484..2165140(-) (letA) [Escherichia coli strain SA31-1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=501656 A7A21_RS10705 WP_000611335.1 2164484..2165140(-) (letA) [Escherichia coli strain SA31-1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486