Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   A7A10_RS10965 Genome accession   NZ_CP076274
Coordinates   2196609..2197265 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain P393-F10     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2191609..2202265
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7A10_RS10935 (A7A10_10900) yecA 2192861..2193526 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  A7A10_RS10955 (A7A10_10920) pgsA 2194175..2194723 (-) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  A7A10_RS10960 (A7A10_10925) uvrC 2194780..2196612 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  A7A10_RS10965 (A7A10_10930) letA 2196609..2197265 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  A7A10_RS26080 - 2197407..2197478 (+) 72 Protein_2161 transcriptional regulator -
  A7A10_RS10970 (A7A10_10935) yecU 2197561..2197737 (+) 177 WP_000590347.1 protein YecU -
  A7A10_RS10975 (A7A10_10940) yecF 2197724..2197948 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  A7A10_RS10980 (A7A10_10945) sdiA 2198015..2198737 (-) 723 WP_001154267.1 transcriptional regulator SdiA -
  A7A10_RS10985 (A7A10_10950) tcyN 2198967..2199719 (-) 753 WP_001272986.1 L-cystine ABC transporter ATP-binding protein TcyN -
  A7A10_RS10990 (A7A10_10955) tcyL 2199716..2200384 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  A7A10_RS10995 (A7A10_10960) dcyD 2200399..2201385 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=501576 A7A10_RS10965 WP_000611335.1 2196609..2197265(-) (letA) [Escherichia coli strain P393-F10]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=501576 A7A10_RS10965 WP_000611335.1 2196609..2197265(-) (letA) [Escherichia coli strain P393-F10]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486