Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   A7A20_RS10495 Genome accession   NZ_CP076259
Coordinates   2144473..2145129 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain WY517-2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2139473..2150129
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7A20_RS10465 (A7A20_10400) yecA 2140724..2141389 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  A7A20_RS10485 (A7A20_10420) pgsA 2142039..2142587 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  A7A20_RS10490 (A7A20_10425) uvrC 2142644..2144476 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  A7A20_RS10495 (A7A20_10430) letA 2144473..2145129 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  A7A20_RS24390 - 2145271..2145342 (+) 72 Protein_2068 transcriptional regulator -
  A7A20_RS10500 (A7A20_10435) yecU 2145425..2145601 (+) 177 WP_001326718.1 protein YecU -
  A7A20_RS10505 (A7A20_10440) yecF 2145588..2145812 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  A7A20_RS10510 (A7A20_10445) sdiA 2145879..2146601 (-) 723 WP_001154276.1 transcriptional regulator SdiA -
  A7A20_RS10515 (A7A20_10450) tcyN 2146831..2147583 (-) 753 WP_053292662.1 L-cystine ABC transporter ATP-binding protein TcyN -
  A7A20_RS10520 (A7A20_10455) tcyL 2147580..2148248 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  A7A20_RS10525 (A7A20_10460) dcyD 2148263..2149249 (-) 987 WP_001128219.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=501100 A7A20_RS10495 WP_000611335.1 2144473..2145129(-) (letA) [Escherichia coli strain WY517-2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=501100 A7A20_RS10495 WP_000611335.1 2144473..2145129(-) (letA) [Escherichia coli strain WY517-2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCAGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486