Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   KE3_RS04660 Genome accession   NC_021900
Coordinates   914265..914927 (-) Length   220 a.a.
NCBI ID   WP_020916724.1    Uniprot ID   A0AB33ALM4
Organism   Streptococcus lutetiensis 033     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 909265..919927
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KE3_RS10460 (KE3_0952) - 909877..910002 (-) 126 WP_020916719.1 helix-turn-helix domain-containing protein -
  KE3_RS10865 (KE3_0953) - 910035..910211 (+) 177 WP_228380520.1 energy-coupling factor transporter transmembrane protein EcfT -
  KE3_RS10570 (KE3_0955) - 910354..910527 (+) 174 WP_004231642.1 hypothetical protein -
  KE3_RS04640 (KE3_0956) - 910550..910858 (+) 309 WP_020916720.1 ATP-binding cassette domain-containing protein -
  KE3_RS04645 (KE3_0957) xerS 911385..912455 (+) 1071 WP_020916721.1 tyrosine recombinase XerS Machinery gene
  KE3_RS04650 (KE3_0958) - 912563..913243 (-) 681 WP_020916722.1 XRE family transcriptional regulator -
  KE3_RS04655 (KE3_0959) - 913321..914268 (-) 948 WP_020916723.1 sensor histidine kinase -
  KE3_RS04660 (KE3_0960) braR 914265..914927 (-) 663 WP_020916724.1 DNA-binding response regulator Regulator
  KE3_RS04665 (KE3_0961) - 915031..917010 (-) 1980 WP_043895031.1 FtsX-like permease family protein -
  KE3_RS04670 (KE3_0962) - 917012..917764 (-) 753 WP_020916726.1 ABC transporter ATP-binding protein -
  KE3_RS04675 (KE3_0963) - 918216..919037 (-) 822 WP_020916727.1 sugar phosphate isomerase/epimerase family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25417.19 Da        Isoelectric Point: 4.9563

>NTDB_id=50045 KE3_RS04660 WP_020916724.1 914265..914927(-) (braR) [Streptococcus lutetiensis 033]
MKQGKIYIVEDDNTIVSLLKQHLSKVYDVYSVNNFRAIKQEIEEITPDLILMDITLPYFNGFYWTTEIRKTMTLPIIFIS
SSDDEMDTVMALNMGGDDFISKPFSLAILDAKISAFLRRAYQFTSDSYQLDEFSLSREGILSNGSKQINLSPTENKILSI
LFEHQNQVVPKEELLEKLWENESFIDQNTLSVNMTRLRKKVQPLGFDRIHTVRGVGYLLK

Nucleotide


Download         Length: 663 bp        

>NTDB_id=50045 KE3_RS04660 WP_020916724.1 914265..914927(-) (braR) [Streptococcus lutetiensis 033]
ATGAAACAAGGAAAAATTTATATCGTAGAAGATGACAATACCATTGTATCCTTATTAAAACAGCATTTAAGCAAAGTTTA
TGATGTCTATAGTGTTAATAATTTTCGTGCGATTAAGCAAGAAATCGAAGAAATCACCCCGGATTTGATTCTAATGGATA
TCACTTTGCCCTATTTTAATGGTTTCTATTGGACGACTGAGATTCGTAAAACCATGACCTTGCCAATCATATTTATTTCA
TCCAGTGATGATGAAATGGATACCGTCATGGCATTGAATATGGGAGGAGATGATTTCATTTCTAAACCCTTCTCATTAGC
CATCTTAGATGCTAAGATATCAGCTTTTTTGCGCAGAGCTTATCAATTCACTTCTGACAGTTATCAACTCGATGAATTTT
CGTTATCCCGTGAAGGAATTCTATCAAATGGGAGTAAGCAAATTAATCTTTCTCCGACTGAAAACAAAATCCTTAGCATT
TTATTTGAACACCAAAATCAAGTGGTGCCAAAGGAAGAGCTGCTAGAGAAATTGTGGGAAAATGAAAGTTTTATTGACCA
AAACACCTTAAGTGTCAACATGACTCGTTTGCGCAAAAAAGTACAACCATTAGGATTTGATCGCATTCATACTGTGAGAG
GAGTCGGCTATCTTCTAAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-219)

Response regulator receiver domain (Response_reg)

(6-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AB33ALM4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.165

99.091

0.477
  vicR Streptococcus mutans UA159

34.783

100

0.364

Multiple sequence alignment