Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JFY28_RS23190 Genome accession   NZ_CP075852
Coordinates   4772723..4773379 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain S19-651     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4767723..4778379
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JFY28_RS23160 (JFY28_023160) dcyD 4768603..4769589 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  JFY28_RS23165 (JFY28_023165) tcyL 4769604..4770272 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  JFY28_RS23170 (JFY28_023170) tcyN 4770269..4771021 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JFY28_RS23175 (JFY28_023175) sdiA 4771251..4771973 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  JFY28_RS23180 (JFY28_023180) yecF 4772040..4772264 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  JFY28_RS23185 (JFY28_023185) yecU 4772251..4772427 (-) 177 WP_000590347.1 protein YecU -
  JFY28_RS27080 - 4772510..4772581 (-) 72 Protein_4564 transcriptional regulator -
  JFY28_RS23190 (JFY28_023190) letA 4772723..4773379 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JFY28_RS23195 (JFY28_023195) uvrC 4773376..4775208 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JFY28_RS23200 (JFY28_023200) pgsA 4775265..4775813 (+) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JFY28_RS23220 (JFY28_023220) yecA 4776462..4777127 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=500200 JFY28_RS23190 WP_000611335.1 4772723..4773379(+) (letA) [Escherichia coli strain S19-651]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=500200 JFY28_RS23190 WP_000611335.1 4772723..4773379(+) (letA) [Escherichia coli strain S19-651]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486