Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   KE3_RS02380 Genome accession   NC_021900
Coordinates   441939..442583 (+) Length   214 a.a.
NCBI ID   WP_020916314.1    Uniprot ID   A0AB33AKG7
Organism   Streptococcus lutetiensis 033     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 436939..447583
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KE3_RS02360 (KE3_0479) - 437490..438227 (+) 738 WP_043894973.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  KE3_RS02365 (KE3_0480) pknB 438227..440137 (+) 1911 WP_020916311.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  KE3_RS02370 (KE3_0481) liaF 440238..440933 (+) 696 WP_020916312.1 cell wall-active antibiotics response protein LiaF -
  KE3_RS02375 (KE3_0482) - 440930..441955 (+) 1026 WP_020916313.1 sensor histidine kinase -
  KE3_RS02380 (KE3_0483) vraR 441939..442583 (+) 645 WP_020916314.1 response regulator Regulator
  KE3_RS11125 (KE3_0484) - 442707..444107 (+) 1401 WP_081048448.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  KE3_RS02390 (KE3_0485) - 444107..444463 (+) 357 WP_020916316.1 S1 RNA-binding domain-containing protein -
  KE3_RS02395 (KE3_0486) cysK 444562..445491 (-) 930 WP_020916317.1 cysteine synthase A -
  KE3_RS02400 (KE3_0487) - 445591..446217 (-) 627 WP_020916318.1 YigZ family protein -
  KE3_RS02405 (KE3_0488) comFA/cflA 446272..447570 (+) 1299 WP_020916319.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24009.84 Da        Isoelectric Point: 5.0404

>NTDB_id=50017 KE3_RS02380 WP_020916314.1 441939..442583(+) (vraR) [Streptococcus lutetiensis 033]
MAQKIRVILVDDHEMVRLGLKSFFNLQPDVEVIGEAGNGIDGIKLALDLKPDVVVMDLVMPEMSGVEATLKLLKEWKEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVARGELAIETEVDKKIKAHDQRPELHEDLTARERDILRLL
AKGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFKHHLVPQDED

Nucleotide


Download         Length: 645 bp        

>NTDB_id=50017 KE3_RS02380 WP_020916314.1 441939..442583(+) (vraR) [Streptococcus lutetiensis 033]
ATGGCCCAGAAAATTAGAGTTATCCTAGTTGATGATCATGAAATGGTGCGTCTTGGTTTGAAAAGTTTTTTTAACTTGCA
ACCAGATGTTGAAGTTATTGGCGAAGCAGGAAATGGAATTGACGGAATTAAACTTGCTTTAGACTTAAAACCAGATGTCG
TAGTGATGGATTTGGTGATGCCTGAAATGAGTGGTGTTGAAGCGACCTTAAAACTCTTAAAAGAGTGGAAAGAAGCTAAA
ATCCTTGTTCTGACATCTTATCTTGATAATGAAAAAATCTATCCAGTTATTGAAGCAGGTGCTAAAGGTTATATGTTAAA
AACATCTAGTGCCGCTGAAATTCTTAACGCTATTCAGAAAGTAGCACGTGGTGAACTAGCAATCGAAACAGAAGTCGATA
AGAAAATCAAAGCACACGATCAAAGACCTGAATTGCATGAGGATTTGACAGCGCGTGAGCGAGATATTTTAAGACTTTTA
GCCAAAGGTTATGATAATCAGACTATTGCTGATGAACTGTTTATTTCGTTAAAAACCGTTAAAACACACGTTTCAAATAT
CTTGGCTAAGCTAGAAGTGGATGACCGTACACAAGCGGTTGTCTATGCCTTTAAGCATCATTTAGTACCGCAAGATGAGG
ATTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-119)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AB33AKG7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.456

96.262

0.495
  degU Bacillus subtilis subsp. subtilis str. 168

37.054

100

0.388

Multiple sequence alignment