Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KKZ13_RS05145 Genome accession   NZ_CP075737
Coordinates   1048018..1048674 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain CPF6     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1043018..1053674
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KKZ13_RS05115 (KKZ13_05105) yecA 1044269..1044934 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  KKZ13_RS05135 (KKZ13_05125) pgsA 1045584..1046132 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KKZ13_RS05140 (KKZ13_05130) uvrC 1046189..1048021 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  KKZ13_RS05145 (KKZ13_05135) letA 1048018..1048674 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KKZ13_RS26000 - 1048816..1048932 (+) 117 WP_001302039.1 hypothetical protein -
  KKZ13_RS05150 (KKZ13_05140) yecU 1048970..1049146 (+) 177 WP_000590347.1 protein YecU -
  KKZ13_RS05155 (KKZ13_05145) yecF 1049133..1049357 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  KKZ13_RS05160 (KKZ13_05150) sdiA 1049425..1050147 (-) 723 WP_001154287.1 transcriptional regulator SdiA -
  KKZ13_RS05165 (KKZ13_05155) tcyN 1050377..1051129 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KKZ13_RS05170 (KKZ13_05160) tcyL 1051126..1051794 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  KKZ13_RS05175 (KKZ13_05165) dcyD 1051809..1052795 (-) 987 WP_001128213.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=500052 KKZ13_RS05145 WP_000611335.1 1048018..1048674(-) (letA) [Escherichia coli strain CPF6]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=500052 KKZ13_RS05145 WP_000611335.1 1048018..1048674(-) (letA) [Escherichia coli strain CPF6]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
TAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCTAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486