Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JFX59_RS00965 Genome accession   NZ_CP075640
Coordinates   188109..188765 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain S19-141     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 183109..193765
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JFX59_RS00935 (JFX59_000935) dcyD 183989..184975 (+) 987 WP_016232143.1 D-cysteine desulfhydrase -
  JFX59_RS00940 (JFX59_000940) tcyL 184990..185658 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  JFX59_RS00945 (JFX59_000945) tcyN 185655..186407 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JFX59_RS00950 (JFX59_000950) sdiA 186637..187359 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  JFX59_RS00955 (JFX59_000955) yecF 187426..187650 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  JFX59_RS00960 (JFX59_000960) yecU 187637..187813 (-) 177 WP_000590347.1 protein YecU -
  JFX59_RS26110 - 187896..187967 (-) 72 Protein_188 transcriptional regulator -
  JFX59_RS00965 (JFX59_000965) letA 188109..188765 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JFX59_RS00970 (JFX59_000970) uvrC 188762..190594 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JFX59_RS00975 (JFX59_000975) pgsA 190651..191199 (+) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JFX59_RS00995 (JFX59_000995) yecA 191848..192513 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=499231 JFX59_RS00965 WP_000611335.1 188109..188765(+) (letA) [Escherichia coli strain S19-141]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=499231 JFX59_RS00965 WP_000611335.1 188109..188765(+) (letA) [Escherichia coli strain S19-141]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486