Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   EC042_RS18985 Genome accession   NC_017626
Coordinates   3793804..3794928 (-) Length   374 a.a.
NCBI ID   WP_000228563.1    Uniprot ID   D3GYR9
Organism   Escherichia coli 042     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 3788804..3799928
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EC042_RS18955 (EC042_3556) yrdA 3790604..3791158 (+) 555 WP_001286215.1 gamma carbonic anhydrase family protein -
  EC042_RS18960 (EC042_3557) yrdB 3791134..3791391 (-) 258 WP_001070558.1 DUF1488 domain-containing protein -
  EC042_RS18965 (EC042_3558) aroE 3791388..3792206 (-) 819 WP_000451231.1 shikimate dehydrogenase -
  EC042_RS18970 (EC042_3559) tsaC 3792211..3792783 (-) 573 WP_014639322.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  EC042_RS18975 (EC042_3560) yrdD 3792788..3793330 (-) 543 WP_001129723.1 type I DNA topoisomerase -
  EC042_RS18980 (EC042_3561) smg 3793359..3793832 (-) 474 WP_000460672.1 DUF494 family protein Smg -
  EC042_RS18985 (EC042_3562) dprA 3793804..3794928 (-) 1125 WP_000228563.1 DNA-protecting protein DprA Machinery gene
  EC042_RS18990 (EC042_3563) def 3795058..3795567 (+) 510 WP_000114984.1 peptide deformylase -
  EC042_RS18995 (EC042_3564) fmt 3795582..3796529 (+) 948 WP_000004454.1 methionyl-tRNA formyltransferase -
  EC042_RS19000 (EC042_3565) rsmB 3796575..3797864 (+) 1290 WP_001309796.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  EC042_RS19005 (EC042_3566) trkA 3797886..3799262 (+) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  EC042_RS19010 (EC042_3567) mscL 3799392..3799802 (+) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40854.84 Da        Isoelectric Point: 6.1804

>NTDB_id=49917 EC042_RS18985 WP_000228563.1 3793804..3794928(-) (dprA) [Escherichia coli 042]
MVDTEIWLRLMSVSSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFLRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVAGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=49917 EC042_RS18985 WP_000228563.1 3793804..3794928(-) (dprA) [Escherichia coli 042]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCGTCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCTGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGCAGGAGAACTGCACGCGTTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT
TGAACAGGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTATAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATTGGGAATCCGGGAAGCGAAGGGCCGCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (DprA_WH)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D3GYR9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.78

98.663

0.481
  dprA Vibrio cholerae strain A1552

49.032

82.888

0.406
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Haemophilus influenzae Rd KW20

44.51

90.107

0.401
  dprA Legionella pneumophila strain ERS1305867

44.242

88.235

0.39

Multiple sequence alignment