Detailed information NTG0498830

Bioinformatically predicted

Overview

• Name: ccrB
• Type: Machinery gene
• Locus tag: ISP08_RS00230
• Genome accession: NZ_CP064056
• Coordinates: 43744..45369 (-)
• Length: 541 a.a.
• NCBI ID: WP_196931174.1
• Uniprot ID: A0A7T1AZY9
• Organism: Staphylococcus lloydii strain 23_2_7_LY
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	44217..46740	43744..45369	flank	-1152

Gene organization within MGE regions

Location: 43744..46740

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ISP08_RS00230 (ISP08_00230)	ccrB	43744..45369 (-)	1626	WP_196931174.1	recombinase family protein	Machinery gene
ISP08_RS00235 (ISP08_00235)	ccrA	45391..46740 (-)	1350	WP_196931175.1	recombinase family protein	Machinery gene

Sequence

Protein

• Length: 541 a.a.
• Molecular weight: 62241.14 Da
• Isoelectric Point: 9.6979

>NTDB_id=498830 ISP08_RS00230 WP_196931174.1 43744..45369(-) (ccrB) [Staphylococcus lloydii strain 23_2_7_LY]
MDKMKKKLVGGYIRVSTERQVEGYSIEGQITQIEQYCQFNGYELVDIYADRGISGKSMNRPELQRMLNDAKNGKLDCVMV
YKTNRLARNTSDLLTIVEELHRQNVEFFSLSERMEVKNSTGKLMLQILASFSEFERNTILENIYTGQHQRALEGYYQGNL
PLGYNNIPDNKKELIINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGNPFSISAVTYILSNPFYIGKIQFAKY
KDWNDKRRKGLNDNPVIAEGKHTPIISQDLWDKVQARKKQVSKKPQVHGKGTNLLTGIIFCEKCGAAYAASNTTNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVIKQVVERVNQENQVDVAALNHDIAYKQQQFDE
INAKLKNLIQTIEDNPDLTSALKPTIHQYETQLNDITNQINQLKQQQNQEKPSYDTKQIALLLQRIFQNIESMDKSQLKA
LYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTSLDEVLLSTSSLFLPQTLFLQI

Nucleotide

• Length: 1626 bp

>NTDB_id=498830 ISP08_RS00230 WP_196931174.1 43744..45369(-) (ccrB) [Staphylococcus lloydii strain 23_2_7_LY]
ATGGATAAAATGAAGAAAAAGCTTGTAGGAGGCTACATTCGCGTGTCCACAGAGAGACAAGTAGAGGGTTATAGCATCGA
GGGGCAAATTACACAAATAGAGCAATATTGCCAATTTAACGGCTATGAACTCGTTGATATATATGCAGATCGGGGTATAT
CAGGAAAATCTATGAACCGTCCTGAATTACAGCGCATGTTAAATGATGCTAAAAATGGAAAATTAGACTGTGTTATGGTT
TATAAAACAAATCGTTTGGCACGTAATACTTCCGATTTACTTACAATCGTCGAAGAACTTCATCGCCAAAATGTTGAATT
TTTTAGCTTGTCTGAACGCATGGAAGTCAAAAATTCAACAGGCAAGTTAATGCTCCAGATACTTGCAAGTTTTTCCGAAT
TTGAAAGAAATACAATTTTAGAGAACATTTACACCGGACAACATCAAAGAGCTTTAGAGGGCTATTATCAAGGCAATCTT
CCATTAGGATATAATAACATACCTGATAATAAAAAAGAATTAATTATTAATCAACATGAAGCTAACATCGTTAAATATAT
CTTTGAATCTTATGCCAAAGGTCATGGTTATCGTAAAATAGCCAATGCACTCAATCATAAAGGTTATGTCACTAAGAAAG
GTAATCCATTTAGTATTTCAGCTGTTACTTATATTCTCTCAAACCCATTCTATATTGGTAAAATTCAATTCGCGAAATAC
AAAGATTGGAATGATAAACGACGTAAAGGCTTGAATGATAATCCAGTGATCGCTGAAGGCAAACACACACCTATTATTAG
TCAAGATTTATGGGATAAAGTACAAGCACGTAAGAAGCAAGTAAGCAAAAAGCCACAAGTGCATGGTAAAGGAACAAATC
TTTTGACAGGAATAATTTTTTGCGAAAAATGTGGTGCGGCATATGCAGCTTCAAATACAACCAATACACTCAAAGACGGT
ACTAAAAAACGCATTCGGTATTATTCATGTAGTAACTTTCGCAACAAAGGATCAAAGGTATGTTCAGCCAATAGTGTTAG
AGCTGATGTTATCGAAAAGTATGTTATGGATCAAATACTCGAAATAGTCAAAAGTGATAAAGTTATCAAACAAGTTGTCG
AACGTGTCAATCAAGAGAATCAAGTCGATGTAGCTGCACTTAACCATGATATTGCTTATAAACAACAACAATTTGATGAA
ATAAACGCTAAATTAAAAAATCTAATTCAAACCATCGAAGACAATCCAGACTTAACATCTGCACTCAAACCAACCATTCA
TCAATATGAAACACAACTGAATGATATTACAAACCAAATTAATCAACTAAAGCAGCAACAAAATCAAGAGAAACCATCTT
ATGATACGAAACAAATCGCTCTCCTATTACAACGAATATTTCAAAACATAGAATCCATGGATAAATCACAACTCAAAGCA
TTATACCTTACGGTCATTGATCGTATCGATATTCGTAAAGATGGGAATCATAAAAAGCAATTCTATGTCACACTCAAGCT
CAATAATGAGATTATTAAACAACTTTTCAATAATACCTCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTTTAC
CTCAAACGCTCTTTCTTCAAATCTAA

Domains

Predicted by InterproScan.

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (294-359)

• Recombinase (Recombinase) (179-279)

• Resolvase, N terminal domain (Resolvase) (11-154)

3D structure

• AlphaFold DB: A0A7T1AZY9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrB	Staphylococcus aureus N315	80.443	100	0.806