Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SSUD12_RS08465 Genome accession   NC_017621
Coordinates   1693353..1694042 (-) Length   229 a.a.
NCBI ID   WP_014638517.1    Uniprot ID   G7SGB8
Organism   Streptococcus suis D12     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1688353..1699042
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSUD12_RS08440 (SSUD12_1701) - 1688824..1689458 (-) 635 Protein_1620 nitroreductase family protein -
  SSUD12_RS08445 (SSUD12_1702) dnaI 1689533..1690432 (-) 900 WP_014636109.1 primosomal protein DnaI -
  SSUD12_RS08450 (SSUD12_1703) - 1690432..1691583 (-) 1152 WP_014638516.1 replication initiation and membrane attachment family protein -
  SSUD12_RS08455 (SSUD12_1704) nrdR 1691570..1692061 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  SSUD12_RS08460 (SSUD12_1705) - 1692133..1693263 (-) 1131 WP_012027644.1 AI-2E family transporter -
  SSUD12_RS08465 (SSUD12_1706) covR 1693353..1694042 (-) 690 WP_014638517.1 DNA-binding response regulator Regulator
  SSUD12_RS08470 (SSUD12_1707) gndA 1694124..1695551 (-) 1428 WP_014638518.1 NADP-dependent phosphogluconate dehydrogenase -
  SSUD12_RS08475 (SSUD12_1708) - 1695648..1696187 (-) 540 WP_014638519.1 YceD family protein -
  SSUD12_RS08480 (SSUD12_1709) trxB 1696197..1697114 (-) 918 WP_014638520.1 thioredoxin-disulfide reductase -
  SSUD12_RS08485 (SSUD12_1710) - 1697128..1697352 (-) 225 WP_014638521.1 DUF4059 family protein -
  SSUD12_RS08490 (SSUD12_1711) - 1697370..1698713 (-) 1344 WP_014638522.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26259.13 Da        Isoelectric Point: 5.3968

>NTDB_id=49799 SSUD12_RS08465 WP_014638517.1 1693353..1694042(-) (covR) [Streptococcus suis D12]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELAAELFAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=49799 SSUD12_RS08465 WP_014638517.1 1693353..1694042(-) (covR) [Streptococcus suis D12]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTGCAGAACTATTTGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTAGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SGB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment