Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   IGI19_RS10140 Genome accession   NZ_CP075462
Coordinates   1972552..1973208 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain NT1F10     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1967552..1978208
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IGI19_RS10110 dcyD 1968431..1969417 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  IGI19_RS10115 tcyL 1969432..1970100 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  IGI19_RS10120 tcyN 1970097..1970849 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  IGI19_RS10125 sdiA 1971079..1971801 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  IGI19_RS10130 yecF 1971869..1972093 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  IGI19_RS10135 yecU 1972080..1972256 (-) 177 WP_000590344.1 protein YecU -
  IGI19_RS24880 - 1972294..1972410 (-) 117 WP_071889271.1 transcriptional regulator -
  IGI19_RS10140 letA 1972552..1973208 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  IGI19_RS10145 uvrC 1973205..1975037 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  IGI19_RS10150 pgsA 1975094..1975642 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IGI19_RS10170 - 1976338..1977078 (-) 741 WP_034167755.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=497984 IGI19_RS10140 WP_000611335.1 1972552..1973208(+) (letA) [Escherichia coli strain NT1F10]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=497984 IGI19_RS10140 WP_000611335.1 1972552..1973208(+) (letA) [Escherichia coli strain NT1F10]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACTTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486