Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   SSUD12_RS04865 Genome accession   NC_017621
Coordinates   959914..961140 (-) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis D12     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 954914..966140
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSUD12_RS04840 (SSUD12_0946) - 955235..956542 (-) 1308 WP_014637950.1 excalibur calcium-binding domain-containing protein -
  SSUD12_RS04845 (SSUD12_0947) - 956677..956859 (+) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  SSUD12_RS04850 (SSUD12_0948) lepA 956909..958741 (-) 1833 WP_014637951.1 translation elongation factor 4 -
  SSUD12_RS04855 (SSUD12_0949) ndk 958837..959250 (-) 414 WP_002943190.1 nucleoside-diphosphate kinase -
  SSUD12_RS04860 (SSUD12_0950) yihA 959273..959860 (-) 588 WP_014637952.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  SSUD12_RS04865 (SSUD12_0951) clpX 959914..961140 (-) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  SSUD12_RS04875 (SSUD12_0953) - 961338..961850 (-) 513 WP_014637953.1 dihydrofolate reductase -
  SSUD12_RS04880 (SSUD12_0954) - 962217..963056 (-) 840 WP_014637954.1 thymidylate synthase -
  SSUD12_RS04885 (SSUD12_0955) - 963109..963411 (-) 303 WP_014637955.1 hypothetical protein -
  SSUD12_RS04890 (SSUD12_0956) - 963423..963701 (-) 279 WP_002934968.1 hypothetical protein -
  SSUD12_RS04895 (SSUD12_0957) - 963827..964786 (-) 960 WP_014637956.1 ROK family glucokinase -
  SSUD12_RS04900 (SSUD12_0958) - 964878..965213 (-) 336 WP_014637957.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=49792 SSUD12_RS04865 WP_002934974.1 959914..961140(-) (clpX) [Streptococcus suis D12]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=49792 SSUD12_RS04865 WP_002934974.1 959914..961140(-) (clpX) [Streptococcus suis D12]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTCATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAACAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTTGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGTATTTTG
ACGGAACCAAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAGACTGGCGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGCCAAGATAACGTTAAACGTGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCTTAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574

Multiple sequence alignment