Detailed information NTG0049707

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: L897_RS07275
• Genome accession: NC_021807
• Coordinates: 1451698..1454526 (-)
• Length: 942 a.a.
• NCBI ID: WP_002993235.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes HSC5
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1446698..1459526

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L897_RS07245 (L897_07420)	-	1447374..1448339 (+)	966	WP_020837630.1	LacI family DNA-binding transcriptional regulator	-
L897_RS07250 (L897_07425)	nusB	1448480..1448932 (-)	453	WP_002988501.1	transcription antitermination factor NusB	-
L897_RS07255 (L897_07430)	-	1448925..1449314 (-)	390	WP_002993228.1	Asp23/Gls24 family envelope stress response protein	-
L897_RS07260 (L897_07435)	efp	1449360..1449917 (-)	558	WP_002988496.1	elongation factor P	-
L897_RS07265 (L897_07440)	-	1450013..1450474 (-)	462	WP_020837633.1	deaminase	-
L897_RS07270 (L897_07445)	-	1450509..1451582 (-)	1074	WP_042361523.1	Xaa-Pro peptidase family protein	-
L897_RS07275 (L897_07450)	uvrA	1451698..1454526 (-)	2829	WP_002993235.1	excinuclease ABC subunit UvrA	Machinery gene
L897_RS07280 (L897_07455)	prx	1454753..1454935 (-)	183	WP_011184907.1	hypothetical protein	Regulator
L897_RS07285 (L897_07460)	sda3	1455173..1455973 (+)	801	WP_011285611.1	streptodornase Sda3	-
L897_RS07290 (L897_07465)	-	1456245..1456679 (+)	435	WP_011017966.1	hypothetical protein	-
L897_RS07295 (L897_07470)	-	1456729..1457595 (-)	867	WP_011888701.1	DUF334 domain-containing protein	-
L897_RS07300 (L897_07475)	-	1457583..1458107 (-)	525	WP_011017840.1	Panacea domain-containing protein	-
L897_RS07305 (L897_07480)	-	1458247..1459449 (-)	1203	WP_020837640.1	glucosaminidase domain-containing protein	-

Sequence

Protein

• Length: 942 a.a.
• Molecular weight: 104112.30 Da
• Isoelectric Point: 6.1170

>NTDB_id=49707 L897_RS07275 WP_002993235.1 1451698..1454526(-) (uvrA) [Streptococcus pyogenes HSC5]
MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL
SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPIVRRKK
GQHKTIFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRLFDSVEAALRLGDGYLMIDTMDG
NELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKSLREGALAPWNPISSNYYPTML
EQAMASFGVDMDTPFEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYTRNVMRGYM
NELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELELTENESTIAKPIVKEIHDRLTFLNNVGLNYL
TLSRAAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLI
DVGPGAGEFGGEIIASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNLQHLDVRFPLGKFIAVT
GVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHIERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALVFF
SAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVD
DGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQIVATGTPEEVAQVKESYTGHYLKVKLQQ

Nucleotide

• Length: 2829 bp

>NTDB_id=49707 L897_RS07275 WP_002993235.1 1451698..1454526(-) (uvrA) [Streptococcus pyogenes HSC5]
ATGCAAAATAAAATAATAATTCATGGGGCAAGAGCCCACAATTTAAAAAATATTGACGTGGAAATTCCACGAGACAAATT
AGTTGTTGTGACAGGGTTATCAGGGTCAGGAAAATCTAGTCTAGCCTTTGATACTATTTATGCGGAAGGGCAACGTCGTT
ACGTAGAAAGTTTATCAGCTTATGCTAGACAGTTCTTGGGTAATATGGAAAAACCAGATGTGGATTCCATTGACGGTCTT
AGCCCTGCTATTTCCATTGATCAAAAAACTACCAGTAAGAACCCCCGCTCAACGGTTGGTACGGTGACTGAAATCAATGA
TTATTTACGTTTACTATATGCGCGTGTGGGCACACCTTACTGTATTAATGGGCATGGGGCCATTACAGCATCTTCTGCAG
AACAAATTGTAGAGCAGGTCTTAGCCCTCCCTGAACGGACACGCATGCAGATTTTAGCGCCTATTGTTCGCCGGAAAAAA
GGTCAACACAAAACCATTTTTGAGAAAATTCAAAAAGATGGCTATGTCCGTGTGCGGGTTGATGGGGATATTTTTGACGT
GACAGAAGTGCCGGAGCTGTCAAAAAGTAAGATGCACAACATCGAGGTGGTTATTGATCGTCTGGTTAATAAGGATGGTA
TTCGTAGCCGTTTATTTGATTCGGTTGAAGCAGCTTTAAGGCTGGGAGATGGCTACCTTATGATTGACACTATGGATGGC
AATGAACTGCTCTTTTCTGAGCATTATTCCTGTCCTGTCTGTGGATTTACGGTTCCTGAATTAGAACCAAGACTCTTCTC
TTTTAATGCGCCGTTCGGCTCTTGTCCGACCTGTGATGGGCTAGGCATTAAGTTGGAAGTGGATTTGGACTTGGTTGTTC
CTGACCCAAGTAAGTCTTTGAGAGAGGGAGCTTTGGCGCCTTGGAATCCTATTTCCTCCAATTATTACCCAACCATGCTT
GAGCAAGCTATGGCAAGTTTTGGGGTGGATATGGATACACCTTTTGAGGCCTTGACTGAGGAAGAAAGAGATTTAGTGCT
TTATGGTTCAGGTGATAGAGAATTTCATTTTCACTATGTGAATGATTTTGGTGGTGAGCGTAACATTGACATTCCTTTTG
AAGGTGTTGTAACTAATGTTAATCGCCGTTATCACGAAACTAATAGTGATTATACGCGCAATGTGATGCGTGGCTACATG
AATGAATTGACTTGTGCGACTTGTCATGGTTACCGTTTGAATGACCAAGCCTTGTGTGTGCATGTGGGTGGCGAAGAAGG
ACCTCATATTGGTCAAATTTCAGAATTATCGATTGCCGACCACTTGCAGTTGTTGGAAGAACTGGAACTCACAGAAAATG
AAAGTACCATTGCTAAACCGATTGTCAAAGAAATTCATGACCGCCTGACCTTCTTAAATAATGTGGGACTGAATTATCTG
ACCTTATCACGGGCTGCTGGGACTTTATCAGGTGGGGAAAGTCAACGAATCAGGTTAGCAACACAAATTGGTTCTAACTT
ATCAGGGGTGCTCTATATCTTGGATGAGCCTTCTATTGGATTGCACCAAAGAGACAATGACCGTTTGATCGAAAGCCTGA
AAAAAATGCGTGATTTGGGTAATACCTTAATTGTGGTAGAACACGATGAAGACACCATGATGCAGGCAGACTGGCTGATT
GATGTGGGACCGGGGGCAGGTGAGTTCGGTGGAGAAATTATTGCCTCTGGAACGCCGAAACAAGTGGCTAAGAATAAAAA
ATCCATCACGGGTCAATATTTGTCTGGTAAAAAATTCATTCCAGTGCCATTAGAGCGTCGTTCTGGTAATGGGCGATTCA
TTGAAATAAAAGGAGCAGCACAGAACAATCTTCAACACCTTGATGTTAGATTCCCACTGGGTAAATTTATTGCTGTTACA
GGGGTATCAGGCTCAGGGAAATCAACCTTGGTTAATAGTATTTTGAAAAAGGCTGTCGCCCAAAAATTAAACCGTAATGC
TGATAAGCCTGGTAAATATCACTCTATTTCTGGTATTGAACATATTGAACGCTTGATTGACATTGACCAAAGTCCGATTG
GAAGGACGCCACGGTCAAATCCAGCCACCTATACGGGTGTCTTTGATGATATTCGAGACTTGTTTGCCCAAACCAACGAA
GCTAAGATTCGTGGTTACAAAAAAGGCCGTTTCTCTTTTAATGTCAAAGGTGGGCGTTGTGAGGCTTGTTCAGGTGATGG
GATTATCAAAATCGAAATGCACTTTTTGCCAGATGTTTATGTGCCTTGTGAGGTTTGCCACGGCAGACGGTATAATTCTG
AGACGCTTGAGGTGCATTATAAAGAAAAAAATATTGCTGAAGTGCTTGACATGACTGTCGATGATGCCTTGGTATTTTTC
TCTGCTATCCCTAAAATTGCCCGAAAAATTCAAACCATTAAGGATGTTGGTTTGGGTTATGTGACCTTGGGTCAACCAGC
TACTACTCTATCTGGAGGAGAAGCGCAGCGGATGAAATTAGCTAGTGAATTGCACAAACGCTCGACAGGTAAGAGCTTGT
ATATCCTAGATGAGCCAACGACTGGTTTACACACAGATGATATTGCAAGGCTATTAAAAGTTTTGGAACGCTTTGTAGAC
GATGGTAATACGGTTCTTGTGATTGAGCATAATTTGGACGTTATCAAATCTGCTGACCATATTATTGACTTAGGACCAGA
AGGTGGTGTCGGAGGTGGTCAGATTGTTGCTACGGGGACACCAGAAGAGGTAGCTCAAGTTAAAGAAAGCTATACTGGTC
ATTATTTGAAAGTAAAACTACAACAATAG

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (624-860)

• UvrA DNA-binding domain (UvrA_DNA-bind) (288-396)

• UvrA interaction domain (UvrA_inter) (132-238)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	84.926	100	0.849
uvrA	Streptococcus pneumoniae TIGR4	84.926	100	0.849
uvrA	Streptococcus pneumoniae D39	84.926	100	0.849