Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KIL87_RS10930 Genome accession   NZ_CP074998
Coordinates   2216046..2216702 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 6883     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2211046..2221702
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KIL87_RS10895 (KIL87_10830) dcyD 2211925..2212911 (+) 987 WP_001128238.1 D-cysteine desulfhydrase -
  KIL87_RS10900 (KIL87_10835) tcyL 2212926..2213594 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KIL87_RS10905 (KIL87_10840) tcyN 2213591..2214343 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KIL87_RS10910 (KIL87_10845) sdiA 2214573..2215295 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  KIL87_RS10915 (KIL87_10850) yecF 2215363..2215587 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KIL87_RS10920 (KIL87_10855) yecU 2215574..2215750 (-) 177 WP_001342215.1 protein YecU -
  KIL87_RS10925 - 2215788..2215904 (-) 117 WP_001302039.1 hypothetical protein -
  KIL87_RS10930 (KIL87_10860) letA 2216046..2216702 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KIL87_RS10935 (KIL87_10865) uvrC 2216699..2218531 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  KIL87_RS10940 (KIL87_10870) pgsA 2218588..2219136 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KIL87_RS10960 (KIL87_10890) - 2220129..2220410 (+) 282 WP_001303543.1 hypothetical protein -
  KIL87_RS10965 (KIL87_10895) - 2220599..2220739 (-) 141 WP_000078921.1 Hok/Gef family protein -
  KIL87_RS10970 (KIL87_10900) - 2220930..2221190 (-) 261 WP_000488107.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=496984 KIL87_RS10930 WP_000611328.1 2216046..2216702(+) (letA) [Escherichia coli strain 6883]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=496984 KIL87_RS10930 WP_000611328.1 2216046..2216702(+) (letA) [Escherichia coli strain 6883]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482