Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   IRE31_RS02020 Genome accession   NZ_CP063829
Coordinates   371742..372431 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 19A-ST320_99-176     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 366742..377431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IRE31_RS01995 (IRE31_01965) gpsB 366839..367180 (+) 342 WP_000200644.1 cell division regulator GpsB -
  IRE31_RS02005 (IRE31_01975) - 367666..368823 (+) 1158 WP_000711398.1 class I SAM-dependent RNA methyltransferase -
  IRE31_RS02010 (IRE31_01980) mapZ 368836..370230 (+) 1395 WP_000039290.1 mid-cell-anchored protein MapZ -
  IRE31_RS02015 (IRE31_01985) gndA 370306..371730 (+) 1425 WP_000158792.1 NADP-dependent phosphogluconate dehydrogenase -
  IRE31_RS02020 (IRE31_01990) covR 371742..372431 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  IRE31_RS02025 (IRE31_01995) cbpC 372529..373491 (+) 963 WP_000698035.1 choline-binding protein CbpC -
  IRE31_RS02030 (IRE31_02000) cbpJ 373510..374508 (+) 999 WP_000771129.1 choline-binding protein CbpJ -
  IRE31_RS02035 (IRE31_02005) - 374626..375858 (-) 1233 WP_000765684.1 MFS transporter -
  IRE31_RS02040 (IRE31_02010) - 376017..376487 (-) 471 WP_001809487.1 lanthionine synthetase LanC family protein -
  IRE31_RS02045 (IRE31_02015) - 376387..376745 (-) 359 Protein_399 lantibiotic-modifying protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=496891 IRE31_RS02020 WP_000518011.1 371742..372431(+) (covR) [Streptococcus pneumoniae strain 19A-ST320_99-176]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=496891 IRE31_RS02020 WP_000518011.1 371742..372431(+) (covR) [Streptococcus pneumoniae strain 19A-ST320_99-176]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467